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Erjie Tian
Researcher at Northeast Agricultural University
Publications - 9
Citations - 214
Erjie Tian is an academic researcher from Northeast Agricultural University. The author has contributed to research in topics: Autophagy & Apoptosis. The author has an hindex of 5, co-authored 7 publications receiving 147 citations.
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Journal ArticleDOI
Colistin-induced autophagy and apoptosis involves the JNK-Bcl2-Bax signaling pathway and JNK-p53-ROS positive feedback loop in PC-12 cells
Ziyin Lu,Yusong Miao,Ishfaq Muhammad,Erjie Tian,Wanjun Hu,Jian Wang,Bo Wang,Rui Li,Jichang Li +8 more
TL;DR: In this article, the role of JNK in colistin-induced neurotoxicity and demonstrated the relationship among JNK, p53 and ROS in PC-12 cells by western blotting, electron microscopy and immunofluorescence/fluorescence microscopy.
Journal ArticleDOI
Baicalin ameliorates oxidative stress and apoptosis by restoring mitochondrial dynamics in the spleen of chickens via the opposite modulation of NF-κB and Nrf2/HO-1 signaling pathway during Mycoplasma gallisepticum infection.
Muhammad Ishfaq,Chunli Chen,Jiaxin Bao,Wei Zhang,Zhiyong Wu,Jian Wang,Yuhao Liu,Erjie Tian,Sattar Hamid,Rui Li,Liangjun Ding,Jichang Li +11 more
TL;DR: Findings indicated that baicalin promoted mitochondrial dynamics imbalance and effectively prevents oxidative stress and apoptosis in the splenocytes of chickens infected with MG.
Journal ArticleDOI
TLR2 mediates autophagy through ERK signaling pathway in Mycoplasma gallisepticum-infected RAW264.7 cells
Ziyin Lu,Daoyuan Xie,Ying Chen,Erjie Tian,Ishfaq Muhammad,Xueping Chen,Yusong Miao,Wanjun Hu,Ziyong Wu,Huili Ni,Jiuqing Xin,Yuan Li,Jichang Li +12 more
TL;DR: It is demonstrated that Toll‐like receptor 2 (TLR2) may mediate MG‐induced autophagy through ERK signaling pathway in macrophage and inhibition of ERK by PD98059 (ERK inhibitor) also significantly attenuated the level of autophage upon MG infection.
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A Dual Role of P53 in Regulating Colistin-Induced Autophagy in PC-12 Cells.
Ziyin Lu,Chunli Chen,Zhiyong Wu,Yusong Miao,Ishfaq Muhammad,Liangjun Ding,Erjie Tian,Wanjun Hu,Huilin Ni,Rui Li,Bo Wang,Jichang Li +11 more
TL;DR: The data supported that silencing of p53 promotes impaired autophagy, which acts as a pro-apoptotic induction factor in PC-12 cells treated with colistin for 24 h, and overexpression of p 53 inhibits autophagic vacuoles and accelerates apoptosis.
Journal ArticleDOI
Population pharmacokinetics for danofloxacin in the intestinal contents of healthy and infected chickens
Erjie Tian,Chunli Chen,Wanjun Hu,Yusong Miao,Ishfaq Muhammad,Qiaomei Zhang,Yuhao Liu,Liang Xu,Jiaxin Bao,Liangjun Ding,Jichang Li +10 more
TL;DR: The PopPK for danofloxacin in infected chicken intestines was quite different from healthy chickens, and the pharmacokinetic characteristics in the intestine of infected chickens changed significantly, which means the ileum can be used as a representative of all intestinal segments.