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Ersell Richardson

Researcher at National Institutes of Health

Publications -  12
Citations -  1739

Ersell Richardson is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Simian immunodeficiency virus & ELISPOT. The author has an hindex of 10, co-authored 12 publications receiving 1706 citations.

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Isolation of human T-cell leukemia virus in acquired immune deficiency syndrome (AIDS)

TL;DR: Whether or not HTLV-I or other retroviruses of this family with T-cell tropism cause AIDS, it is possible that patients from whom the virus can be isolated can also transmit it to others.
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An adenovirus-simian immunodeficiency virus env vaccine elicits humoral, cellular, and mucosal immune responses in rhesus macaques and decreases viral burden following vaginal challenge.

TL;DR: It is shown that a vaccine regimen using the Ad5hr-SIV env recombinant and gp120 subunit induces strong humoral, cellular, and mucosal immunity in rhesus macaques, and supports further development of Ad-based vaccines comprising additional viral components for immune therapy and AIDS vaccine development.
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Potent, Persistent Induction and Modulation of Cellular Immune Responses in Rhesus Macaques Primed with Ad5hr-Simian Immunodeficiency Virus (SIV) env/rev, gag, and/or nef Vaccines and Boosted with SIV gp120

TL;DR: Immunity elicited by multicomponent vaccines delivered by replication-competent Ad5hr-simian immunodeficiency virus (SIV) recombinants was systematically investigated and modulation of this cellular immune response was observed among macaques receiving one, two, or three Ad5HR-SIV recombinant
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Factors Associated with Slow Disease Progression in Macaques Immunized with an Adenovirus-Simian Immunodeficiency Virus (SIV) Envelope Priming-gp120 Boosting Regimen and Challenged Vaginally with SIVmac251

TL;DR: The partial protection against a virulent, pathogenic SIV challenge observed in two of six macaques immunized with a vaccine regimen based solely on the viral envelope indicates that this vectored-vaccine approach has promise and that multicomponent vaccines based in the same system merit further investigation.