E
Esa Hämäläinen
Researcher at University of Helsinki
Publications - 176
Citations - 7010
Esa Hämäläinen is an academic researcher from University of Helsinki. The author has contributed to research in topics: Pregnancy & Estrogen. The author has an hindex of 38, co-authored 166 publications receiving 5958 citations. Previous affiliations of Esa Hämäläinen include Helsinki University Central Hospital & Boston Children's Hospital.
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Journal ArticleDOI
Soybean phytoestrogen intake and cancer risk.
C H Adlercreutz,Barry R. Goldin,Sherwood L. Gorbach,K A Höckerstedt,Shaw Watanabe,Esa Hämäläinen,M H Markkanen,T H Mäkelä,Kristiina Wähälä,T Adlercreutz +9 more
TL;DR: Results are reviewed that suggest that the diphenolic isoflavonoids and lignans are natural cancer-protective compounds.
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Effect of dietary components, including lignans and phytoestrogens, on enterohepatic circulation and liver metabolism of estrogens and on sex hormone binding globulin (SHBG).
Herman Adlercreutz,Krister Höckerstedt,C. Bannwart,S. Bloigu,Esa Hämäläinen,Theodore Fotsis,A. Ollus +6 more
TL;DR: It is concluded that dietary macro- and micronutrients seem to play an important role in estrogen metabolism, and fiber intake and urinary excretion of lignans and phytoestrogens, and the concentration of plasma SHBG in women.
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Dietary phytoestrogens and cancer: in vitro and in vivo studies.
Herman Adlercreutz,Yaghoob Mousavi,James H. Clark,Krister Höckerstedt,Esa Hämäläinen,Kristiina Wähälä,Taru Mäkelä,Tapio Hase +7 more
TL;DR: It is suggested that lignans and isoflavonoids may affect uptake and metabolism of sex hormones by participating in the regulation of plasma SHBG levels and in this way influence their biological activity and that they may inhibit cancer cell growth like some flavonoids by competing with estradiol for the type II estrogen binding sites.
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Dietary phyto-oestrogens and the menopause in Japan.
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Estrogen metabolism and excretion in Oriental and Caucasian women
Herman Adlercreutz,Sherwood L. Gorbach,Barry R. Goldin,Margo N. Woods,Johanna T. Dwyer,Esa Hämäläinen +5 more
TL;DR: The results indicate that high catechol estrogen formation may be a greater risk factor for breast cancer than high 16 alpha-hydroxylation of estrogens, but the main risk factors for the Finnish women, as opposed to the Oriental women, may be their higher estrogen levels that result from a higher fat diet, higher estrogen production related to their greater height, and lower fecal estrogen excretion.