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Eva Cecilie Bonefeld-Jørgensen
Researcher at Aarhus University
Publications - 163
Citations - 7781
Eva Cecilie Bonefeld-Jørgensen is an academic researcher from Aarhus University. The author has contributed to research in topics: Population & Environmental exposure. The author has an hindex of 44, co-authored 154 publications receiving 6670 citations. Previous affiliations of Eva Cecilie Bonefeld-Jørgensen include Health Science University & University of Greenland.
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Journal ArticleDOI
Effects of currently used pesticides in assays for estrogenicity, androgenicity, and aromatase activity in vitro.
Helle Raun Andersen,Anne Marie Vinggaard,Thomas Høj Rasmussen,Irene M. Gjermandsen,Eva Cecilie Bonefeld-Jørgensen +4 more
TL;DR: The potencies of the pesticides to react as hormone agonists or antagonists are low compared to the natural ligands, but the integrated response in the organism might be amplified by the ability of the pesticide to act via several mechanism and the frequent simultaneous exposure to several pesticides.
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Endocrine-disrupting potential of bisphenol A, bisphenol A dimethacrylate, 4-n-nonylphenol, and 4-n-octylphenol in vitro: new data and a brief review.
TL;DR: In vitro data clearly indicate that the four industrial compounds have ED potentials and that the effects can be mediated via several cellular pathways, including the two sex steroid hormone receptors (ER and AR), aromatase activity converting testosterone to estrogen, and AhR; AhR is involved in syntheses of steroid and metabolism of steroids and xenobiotic compounds.
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Effect of highly bioaccumulated polychlorinated biphenyl congeners on estrogen and androgen receptor activity.
Eva Cecilie Bonefeld-Jørgensen,Helle Raun Andersen,Thomas Høj Rasmussen,Anne Marie Vinggaard +3 more
TL;DR: Evidence is presented that the di-ortho, multiple-chloro substituted biphenyls, PCB #138, PCB#153 and PCB#180, can compete with the binding of the natural ligand to two nuclear receptors and thus possess the ability to interfere with sexual hormone regulated processes.
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Global DNA hypomethylation is associated with high serum-persistent organic pollutants in Greenlandic Inuit.
Jennifer A. Rusiecki,Andrea A. Baccarelli,Valentina Bollati,Letizia Tarantini,Lee E. Moore,Eva Cecilie Bonefeld-Jørgensen +5 more
TL;DR: In inverse correlations between percents methylcytosine and many of the POP concentrations measured, global methylation levels were inversely associated with blood plasma levels for several POPs and merit further investigation.
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Effects of plasticizers and their mixtures on estrogen receptor and thyroid hormone functions.
TL;DR: The tested plasticizers and phenols elicited endocrine-disrupting potential that can be mediated via interference with the estrogen and TH systems, and the observed mixture effect stresses the importance of considering the combined effect of the compounds for risk assessment of human health.