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Eva Latulippe
Researcher at Memorial Sloan Kettering Cancer Center
Publications - 8
Citations - 3286
Eva Latulippe is an academic researcher from Memorial Sloan Kettering Cancer Center. The author has contributed to research in topics: Prostate cancer & Medicine. The author has an hindex of 5, co-authored 5 publications receiving 3204 citations.
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Journal ArticleDOI
Multiclass cancer diagnosis using tumor gene expression signatures
Sridhar Ramaswamy,Pablo Tamayo,Ryan Rifkin,Sayan Mukherjee,Chen-Hsiang Yeang,Michael Angelo,Christine Ladd,Michael Reich,Eva Latulippe,Jill P. Mesirov,Tomaso Poggio,William L. Gerald,Massimo Loda,Eric S. Lander,Todd R. Golub,Todd R. Golub +15 more
TL;DR: The results demonstrate the feasibility of accurate, multiclass molecular cancer classification and suggest a strategy for future clinical implementation of molecular cancer diagnostics.
Journal ArticleDOI
Gene Expression Analysis of Human Prostate Carcinoma during Hormonal Therapy Identifies Androgen-Responsive Genes and Mechanisms of Therapy Resistance
Jeff Holzbeierlein,Priti Lal,Eva Latulippe,Alex Smith,Jaya M. Satagopan,Liying Zhang,Charles J. Ryan,Steve Smith,Howard I. Scher,Howard I. Scher,Peter T. Scardino,Victor E. Reuter,William L. Gerald +12 more
TL;DR: A genome-wide expression analysis of human prostate cancer during androgen ablation therapy to identify genes regulated by androgen and genes differentially expressed after the development of resistance suggested that resistant tumors have increased sensitivity to and endogenous synthesis of androgenic hormones.
Journal Article
Comprehensive gene expression analysis of prostate cancer reveals distinct transcriptional programs associated with metastatic disease.
Eva Latulippe,Jaya M. Satagopan,Alex Smith,Howard I. Scher,Peter T. Scardino,Victor E. Reuter,William L. Gerald +6 more
TL;DR: A strong correlation between high proliferation rates in metastatic cancers and overexpression of genes that participate in cell cycle regulation, DNA replication, and DNA repair and other functional categories of differentially expressed genes included transcriptional regulation, signaling, signal transduction, cell structure, and motility.
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Accelerated Induction of Bladder Cancer in Patched Heterozygous Mutant Mice
Sahar Hamed,Hélène LaRue,Hélène Hovington,Johanne Girard,Lucie Jeannotte,Eva Latulippe,Yves Fradet +6 more
TL;DR: The hypothesis of PTC acting as a tumor suppressor gene in bladder cancer is supported by data submitted Ptc+/− heterozygous mutant mice and their wild-type littermates to chemical carcinogenesis by adding N-butyl-N-(4-hydroxybutyl) nitrosamine to their drinking water.
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Improved cancer specific-survival in patients with carcinoma invading bladder muscle expressing cyclo-oxygenase-2.
Anis Aziz,Annie Lessard,Kate H. Moore,Hélène Hovington,Eva Latulippe,Hélène LaRue,Yves Fradet,Louis Lacombe +7 more
TL;DR: In this paper, the expression of COX-2 was evaluated immunohistochemically with a monoclonal anti-COX-1 antibody and showed an increased disease-specific survival (P= 0.0063), as well as longer recurrence-free survival and a tendency was also observed in a subgroup with positive nodes treated with adjuvant chemotherapy.