Ezio Bolzacchini

TL;DR: The results underline that the in vitro responsiveness to PM may be cell line dependent and suggest that the PM different properties may trigger different endpoints such as inflammation, perturbation of cell cycle and cell death.

TL;DR: The different seasonal chemical composition of PM showed to influence some biological properties, which were investigated by bivariate analysis and multivariate data analysis to investigate the relationship between PM chemical composition and the biological effects produced by cell exposure to 12 microg cm(-2).

TL;DR: In Milan (MI), the largest city in Northern Italy, the annually average PM2.5 concentration is above 25 μg m(-3), the value that the EU established as a target for 2010, and the upper limit from 2015 onwards (2008/30/CE).

TL;DR: In this article, seven HPLC columns were used for the optimization of the isocratic HPLC measurement of phenol, nitro-and dinitrophenols in liquid and in gas phase in the laboratory.

TL;DR: A significant intracellular production of reactive oxygen species (ROS) was observed, suggesting that the cytotoxicity, exerted by the winter PM(2.5) in Milan, derived also from its oxidative potential, probably associated with particle-adsorbed metals and PAHs.