F
F. J. Burt
Researcher at University of the Witwatersrand
Publications - 5
Citations - 551
F. J. Burt is an academic researcher from University of the Witwatersrand. The author has contributed to research in topics: Antibody & Serology. The author has an hindex of 5, co-authored 5 publications receiving 524 citations.
Papers
More filters
Journal Article
Immunohistochemical and in situ localization of Crimean-Congo hemorrhagic fever (CCHF) virus in human tissues and implications for CCHF pathogenesis.
F. J. Burt,R. Swanepoel,Wun-Ju Shieh,Jonathan F. Smith,P. A. Leman,Patricia W. Greer,L M Coffield,Pierre E. Rollin,Thomas G. Ksiazek,Clarence J. Peters,Sherif R. Zaki +10 more
TL;DR: In this article, the authors conducted a case analysis of 12 patients with a diagnosis of CCHF infection, confirmed by virus isolation, who were evaluated at the Special Pathogens Unit, National Institute for Virology, South Africa.
Journal ArticleDOI
The use of a reverse transcription–polymerase chain reaction for the detection of viral nucleic acid in the diagnosis of Crimean–Congo haemorrhagic fever
TL;DR: Early in the disease there is relatively good correlation between the results obtained by RT-PCR and virus isolation, but after the first week it appears that infective virus is progressively cleared from serum while nucleic acid remains demonstrable in a proportion of patients well into convalescence.
Journal ArticleDOI
Serodiagnosis of Crimean-Congo haemorrhagic fever.
TL;DR: It was concluded that the IF tests were most convenient for use in making a rapid serodiagnosis of the Crimean-Congo haemorrhagic fever virus.
Journal ArticleDOI
Investigation of tick-borne viruses as pathogens of humans in South Africa and evidence of Dugbe virus infection in a patient with prolonged thrombocytopenia.
TL;DR: The CCHF findings confirmed previous observations that the virus is widely prevalent within the distribution range of ticks of the genus Hyalomma, while antibody activity to Dugbe antigen was detected only within the Distribution range of the tick Amblyomma hebraeum.
Journal ArticleDOI
Enzyme-linked immunosorbent assays for the detection of antibody to Crimean-Congo haemorrhagic fever virus in the sera of livestock and wild vertebrates.
TL;DR: The prevalence of antibody was found to be greatest in large mammals such as rhinoceros, giraffe and buffalo, which are known to be the preferred hosts of the adult tick (Hyalomma) vectors of the virus.