F
Fabien Aubry
Researcher at Pasteur Institute
Publications - 24
Citations - 642
Fabien Aubry is an academic researcher from Pasteur Institute. The author has contributed to research in topics: Virus & Zika virus. The author has an hindex of 11, co-authored 24 publications receiving 434 citations. Previous affiliations of Fabien Aubry include EHESP & Centre national de la recherche scientifique.
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Flavivirus reverse genetic systems, construction techniques and applications: a historical perspective.
TL;DR: This review summarizes the evolution and major technical breakthroughs in the development of flavivirus reverse genetics technologies and their application to the further understanding and control of these viruses and their diseases.
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Single-stranded positive-sense RNA viruses generated in days using infectious subgenomic amplicons.
Fabien Aubry,Antoine Nougairède,Lauriane de Fabritus,Gilles Querat,Ernest A. Gould,Xavier de Lamballerie +5 more
TL;DR: Both wild-type and genetically modified infectious RNA viruses were generated in days using the newly described ISA (infectious-subgenomic-amplicons) method, and this new versatile and simple procedure may enhance the capacity to obtain infectiousRNA viruses from PCR-AMplified genetic material.
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Random Codon Re-encoding Induces Stable Reduction of Replicative Fitness of Chikungunya Virus in Primate and Mosquito Cells
Antoine Nougairède,Lauriane de Fabritus,Fabien Aubry,Ernest A. Gould,Edward C. Holmes,Edward C. Holmes,Xavier de Lamballerie +6 more
TL;DR: Random codon re-encoding provides important information on the evolution and genetic stability of Chikungunya virus and could be exploited to develop a safe, live attenuated CHIKV vaccine.
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Recent African strains of Zika virus display higher transmissibility and fetal pathogenicity than Asian strains
Fabien Aubry,Sofie Jacobs,Maïlis Darmuzey,Sebastian Lequime,Sebastian Lequime,Leen Delang,Albin Fontaine,Natapong Jupatanakul,Natapong Jupatanakul,Elliott F. Miot,Stéphanie Dabo,Caroline Manet,Xavier Montagutelli,Artem Baidaliuk,Fabiana Gámbaro,Etienne Simon-Loriere,Maxime Gilsoul,Claudia M. E. Romero-Vivas,Van-Mai Cao-Lormeau,Richard G. Jarman,Cheikh Tidiane Diagne,Oumar Faye,Ousmane Faye,Amadou A. Sall,Johan Neyts,Laurent Nguyen,Suzanne J.F. Kaptein,Louis Lambrechts +27 more
TL;DR: In this article, the authors compared seven low-passage ZIKV strains representing the recently circulating viral genetic diversity and found that these African ZIKVs display higher transmissibility in mosquitoes and higher lethality in both adult and fetal mice than their Asian counterparts.
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Cell-Fusing Agent Virus Reduces Arbovirus Dissemination in Aedes aegypti Mosquitoes In Vivo.
Artem Baidaliuk,Artem Baidaliuk,Elliott F. Miot,Elliott F. Miot,Sebastian Lequime,Isabelle Moltini-Conclois,Fanny Delaigue,Stéphanie Dabo,Laura B. Dickson,Fabien Aubry,Sarah H. Merkling,Van-Mai Cao-Lormeau,Louis Lambrechts +12 more
TL;DR: Results support the idea that insect-only viruses in nature can modulate the ability of mosquitoes to carry arboviruses of medical significance and that they could possibly be manipulated to reduce arBovirus transmission.