Fabienne Hans

TL;DR: A novel hypothesis, termed the ‘ready production label’ model, explains the results in the literature and suggests that phosphorylation of histone H3 is a part of a complex signaling mechanism.

TL;DR: Evidence is presented that the presence of mH2A in a positioned nucleosome interferes with the binding of the transcription factor NF-kappaB and the nonhistone region of mh2A was identified to be associated with this interference.

TL;DR: Nucleolin possesses a histone chaperone activity and this factor greatly enhances the activity of the chromatin remodeling machineries SWI/SNF and ACF, and nucleolin facilitates transcription through the nucleosome, which is reminiscent of theActivity of the FACT complex.

TL;DR: It is postulate that the HIV-1 transactivator, Tat, in targeting Tip60 hinders the expression of cellular genes (such as Mn-SOD) which normally interfere with the efficient replication and propagation of the virus.

TL;DR: It is shown that H2ABbd can replace the conventional H2A in the nucleosome, but this replacement results in alterations of theucleosomal structure.