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Fabiola M. Ribeiro

Researcher at Universidade Federal de Minas Gerais

Publications -  92
Citations -  3517

Fabiola M. Ribeiro is an academic researcher from Universidade Federal de Minas Gerais. The author has contributed to research in topics: Metabotropic glutamate receptor 5 & Neuroprotection. The author has an hindex of 28, co-authored 85 publications receiving 2580 citations. Previous affiliations of Fabiola M. Ribeiro include Robarts Research Institute & University of Western Ontario.

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Alzheimer's disease: Targeting the Cholinergic System

TL;DR: Synthesis of cholinergic neurons located in the basal forebrain, including the neurons that form the nucleus basalis of Meynert, are severely lost in Alzheimer’s disease, and drugs that act on the choline system represent a promising option to treat AD patients.
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Metabotropic glutamate receptors and neurodegenerative diseases.

TL;DR: MGluR knockout mouse models have been crossed to mouse models of AD and HD, providing important data about mGluRs role in neurodegenerative disease progression, and potential therapeutic targets for the development of therapies to treat neurodegenersative diseases are discussed.
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Group I metabotropic glutamate receptor signalling and its implication in neurological disease.

TL;DR: A better understanding of alterations in mGluR signalling in brain disorders will be required in order to discern the molecular and cellular basis of these pathologies.
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Metabotropic Glutamate Receptor-Mediated Cell Signaling Pathways Are Altered in a Mouse Model of Huntington's Disease

TL;DR: It is demonstrated that group I mGluR-mediated signaling pathways are altered in HD and that these cell signaling adaptations could be important for striatal neurons survival.
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The “ins” and “outs” of the high‐affinity choline transporter CHT1

TL;DR: Future investigations of CHT1 trafficking should elucidate such regulatory mechanisms, which may aid in understanding the pathophysiology of diseases that affect cholinergic neurons, such as Alzheimer's disease.