F
Fangfang Chen
Researcher at Chinese Academy of Sciences
Publications - 14
Citations - 396
Fangfang Chen is an academic researcher from Chinese Academy of Sciences. The author has contributed to research in topics: Gene & Mutant. The author has an hindex of 8, co-authored 14 publications receiving 305 citations. Previous affiliations of Fangfang Chen include Huazhong Agricultural University & Hubei University.
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Journal ArticleDOI
MetDIA: Targeted Metabolite Extraction of Multiplexed MS/MS Spectra Generated by Data-Independent Acquisition
TL;DR: Comparisons of the MetDIA method with data-dependent acquisition (DDA) method demonstrated that MetDia could significantly detect more metabolites in biological samples, and is more accurate and sensitive for metabolite identifications.
Journal ArticleDOI
Disruption of the chitin synthase gene CHS1 from Fusarium asiaticum results in an altered structure of cell walls and reduced virulence.
Yu-Bin Xu,He-Ping Li,Jing-Bo Zhang,Bo Song,Fangfang Chen,Xiao-Jun Duan,Huai-Qian Xu,Yu-Cai Liao +7 more
TL;DR: Re-introduction of a functional CHS1 gene into the Deltachs1 mutant strain restored the wild-type phenotype and reveal an important in vivo role played by a CHS 1 gene in a FHB pathogen whose mycelial chitin could serve as a target for controlling the disease.
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Combined metabonomic and quantitative real-time PCR analyses reveal systems metabolic changes of Fusarium graminearum induced by Tri5 gene deletion.
TL;DR: It is shown that Tri5 gene deletion induces widespread changes in FG primary metabolism and the combination of NMR-based metabonomics and qRT-PCR analyses are demonstrated as a useful way to understand the systems metabolic changes resulting from a single specific gene knockout in an eukaryotic genome.
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A vitamin-C-derived DNA modification catalysed by an algal TET homologue
Jian Huang Xue,Guo Dong Chen,Fuhua Hao,Hui Chen,Hui Chen,Zhaoyuan Fang,Fangfang Chen,Bo Pang,Qing Lin Yang,Xinben Wei,Qiang Qiang Fan,Qiang Qiang Fan,Changpeng Xin,Jiaohong Zhao,Xuan Deng,Bang-An Wang,Xiao Jie Zhang,Yueying Chu,Hui Tang,Huiyong Yin,Huiyong Yin,Weimin Ma,Luonan Chen,Luonan Chen,Jianping Ding,Elmar Weinhold,Rahul M. Kohli,Wen Liu,Zheng-Jiang Zhu,Kaiyao Huang,Huiru Tang,Huiru Tang,Guoliang Xu,Guoliang Xu +33 more
TL;DR: In this paper, the green alga Chlamydomonas reinhardtii contains a 5mC-modifying enzyme (CMD1) that is a TET homologue and catalyses the conjugation of a glyceryl moiety to the methyl group of 5mCs through a carbon-carbon bond, resulting in two stereoisomeric nucleobase products.
Journal ArticleDOI
Natural occurrence of fusarium head blight, mycotoxins and mycotoxin-producing isolates of Fusarium in commercial fields of wheat in Hubei
Jing-Bo Zhang,Jian-Hua Wang,An-Dong Gong,Fangfang Chen,Bo Song,Xinyun Li,He-Ping Li,C.-H. Peng,Yu-Cai Liao +8 more
TL;DR: The importance of chemotyping coupled with species identification for improved prediction of mycotoxin contamination in wheat is suggested, and a preferential biosynthesis of 3-AcDON and 4-AcNIV in rice is revealed.