F
Farnaz Asayesh
Researcher at Montreal Neurological Institute and Hospital
Publications - 8
Citations - 70
Farnaz Asayesh is an academic researcher from Montreal Neurological Institute and Hospital. The author has contributed to research in topics: NPC1 & Spinocerebellar ataxia. The author has an hindex of 4, co-authored 8 publications receiving 31 citations. Previous affiliations of Farnaz Asayesh include McGill University.
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Journal ArticleDOI
Association study of DNAJC13, UCHL1, HTRA2, GIGYF2, and EIF4G1 with Parkinson's disease.
Prabhjyot Saini,Uladzislau Rudakou,Eric Yu,Jennifer A. Ruskey,Farnaz Asayesh,Sandra B. Laurent,Dan Spiegelman,Stanley Fahn,Cheryl Waters,Oury Monchi,Yves Dauvilliers,Nicolas Dupré,Lior Greenbaum,Sharon Hassin-Baer,Alberto J. Espay,Guy A. Rouleau,Roy N. Alcalay,Edward A. Fon,Ronald B. Postuma,Ziv Gan-Or,Ziv Gan-Or +20 more
TL;DR: The results do not support an association between any of the 5 tested genes with Parkinson's disease, and it is unlikely that any of these genes plays an important role in PD.
Journal ArticleDOI
Variants in the Niemann-Pick type C gene NPC1 are not associated with Parkinson's disease.
Bouchra Ouled Amar Bencheikh,Konstantin Senkevich,Uladzislau Rudakou,Eric Yu,Kheireddin Mufti,Jennifer A. Ruskey,Farnaz Asayesh,Sandra B. Laurent,Dan Spiegelman,Stanley Fahn,Cheryl Waters,Oury Monchi,Yves Dauvilliers,Alberto J. Espay,Nicolas Dupré,Lior Greenbaum,Sharon Hassin-Baer,Guy A. Rouleau,Roy N. Alcalay,Edward A. Fon,Ziv Gan-Or,Ziv Gan-Or +21 more
TL;DR: The results do not support a link between heterozygous variants in NPC1 and PD and common and rare NPC1 variants were not associated with PD.
Journal ArticleDOI
LRRK2 p.M1646T is associated with glucocerebrosidase activity and with Parkinson's disease
Yuri L. Sosero,Eric Yu,Lynne Krohn,Uladzislau Rudakou,Kheireddin Mufti,Jennifer A. Ruskey,Farnaz Asayesh,Sandra B. Laurent,Dan Spiegelman,Stanley Fahn,Cheryl Waters,S. Pablo Sardi,Sara Bandres-Ciga,Roy N. Alcalay,Ziv Gan-Or,Konstantin Senkevich,Konstantin Senkevich +16 more
TL;DR: The results suggest that the p.M1646T variant is associated with risk of PD with a small effect and with increased GCase activity in peripheral blood.
Journal ArticleDOI
Evidence for Non-Mendelian Inheritance in Spastic Paraplegia 7.
Mehrdad Asghari Estiar,Mehrdad Asghari Estiar,Eric Yu,Eric Yu,Ikhlass Haj Salem,Jay P. Ross,Jay P. Ross,Kheireddin Mufti,Kheireddin Mufti,Fulya Akçimen,Fulya Akçimen,Etienne Leveille,Dan Spiegelman,Jennifer A. Ruskey,Farnaz Asayesh,Alain Dagher,Grace Yoon,Mark A. Tarnopolsky,Kym M. Boycott,Nicolas Dupré,Patrick A. Dion,Patrick A. Dion,Oksana Suchowersky,Jean-François Trempe,Guy A. Rouleau,Guy A. Rouleau,Ziv Gan-Or,Ziv Gan-Or +27 more
TL;DR: In this paper, the authors conducted an exome-wide genetic analysis on a large Canadian cohort of hereditary spastic paraplegia patients and controls to examine the association of SPG7 and HSP.
Posted ContentDOI
Variants in the Niemann-Pick type C gene NPC1 are not associated with Parkinson’s disease
Bouchra Ouled Amar Bencheikh,Bouchra Ouled Amar Bencheikh,Konstantin Senkevich,Konstantin Senkevich,Uladzislau Rudakou,Uladzislau Rudakou,Eric Yu,Eric Yu,Kheireddin Mufti,Kheireddin Mufti,Jennifer A. Ruskey,Jennifer A. Ruskey,Farnaz Asayesh,Farnaz Asayesh,Sandra B. Laurent,Sandra B. Laurent,Dan Spiegelman,Stanley Fahn,Cheryl Waters,Oury Monchi,Oury Monchi,Oury Monchi,Yves Dauvilliers,Alberto J. Espay,Nicolas Dupré,Lior Greenbaum,Lior Greenbaum,Sharon Hassin-Baer,Sharon Hassin-Baer,Guy A. Rouleau,Guy A. Rouleau,Roy N. Alcalay,Edward A. Fon,Edward A. Fon,Ziv Gan-Or,Ziv Gan-Or +35 more
TL;DR: The results do not support a link between heterozygous variants in NPC1 and PD and common and rare NPC1 variants were not associated with PD.