F
Faroudy Boufassa
Researcher at Université Paris-Saclay
Publications - 122
Citations - 7243
Faroudy Boufassa is an academic researcher from Université Paris-Saclay. The author has contributed to research in topics: Viral load & Acquired immunodeficiency syndrome (AIDS). The author has an hindex of 38, co-authored 111 publications receiving 6608 citations. Previous affiliations of Faroudy Boufassa include Institut Gustave Roussy & University of Paris.
Papers
More filters
Journal ArticleDOI
Post-treatment HIV-1 controllers with a long-term virological remission after the interruption of early initiated antiretroviral therapy ANRS VISCONTI Study.
Asier Sáez-Cirión,Charline Bacchus,Laurent Hocqueloux,Véronique Avettand-Fenoel,Isabelle Girault,Camille Lécuroux,Valérie Potard,Pierre Versmisse,Adeline Mélard,Thierry Prazuck,Benjamin Descours,Julien Guergnon,Jean-Paul Viard,Faroudy Boufassa,Olivier Lambotte,Cécile Goujard,Laurence Meyer,Dominique Costagliola,Alain Venet,Gianfranco Pancino,Brigitte Autran,Christine Rouzioux +21 more
TL;DR: The results show that early and prolonged cART may allow some individuals with a rather unfavorable background to achieve long-term infection control and may have important implications in the search for a functional HIV cure.
Journal ArticleDOI
HIV controllers exhibit potent CD8 T cell capacity to suppress HIV infection ex vivo and peculiar cytotoxic T lymphocyte activation phenotype.
Asier Sáez-Cirión,Christine Lacabaratz,Olivier Lambotte,Pierre Versmisse,Alejandra Urrutia,Faroudy Boufassa,Françoise Barré-Sinoussi,Jean-François Delfraissy,Martine Sinet,Gianfranco Pancino,Alain Venet +10 more
TL;DR: Although CD4+ T cells from HIC were fully susceptible to HIV-1 superinfection, their CD8- T cells effectively suppressed HIV- 1 infection, indicating an HLA-restricted cytotoxic mechanism that could account for the control of viral replication in HIC.
Journal ArticleDOI
Time from HIV-1 seroconversion to AIDS and death before widespread use of highly-active antiretroviral therapy: a collaborative re-analysis
A Babiker,S Darby,Daniela De Angelis,D Kwart,Kholoud Porter,Beral,JH Darbyshire,Nicholas E. Day,Noel Gill,Roel A. Coutinho,Maria Prins,B van Benthem,François Dabis,C Marimoutou,I Ruiz,J M Tusell,C Altisent,B Evatt,Harold W. Jaffe,Ole Kirk,C.B. Pedersen,P Rosenberg,James J. Goedert,Robert J. Biggar,Mads Melbye,R Brettie,A Downs,Osamah Hamouda,Giota Touloumi,Anastasia Karafoulidou,Olga Katsarou,S Donfield,E Gomperts,M Hilgartner,K Hoots,E Schoenbaum,R Zangerle,J Del Amo,P Pezzotti,G. Rezza,S Hutchinson,Sheila M. Gore,L Kingsley,L Schrager,S Melnick,Beryl A. Koblin,Anne Eskild,Johan N. Bruun,Mette Sannes,Barry Evans,Alessandro Cozzi Lepri,CA Sabin,Susan Buchbinder,Eric Vittinghoff,A Moss,D Osmond,W Winkelstein,David J. Goldberg,Faroudy Boufassa,Laurence Meyer,Matthias Egger,Patrick Francioli,Martin Rickenbach,David A. Cooper,B Tindall,T Sharkey,Jeanette Vizzard,John M. Kaldor,P Cunningham,Philippe Vanhems,J Learmont,Farewell,O Berglund,J Mosley,E Operskalski,M.A.M.C. van den Berg,David S. Metzger,D Tobin,George E. Woody,J Rusnak,C Hendrix,R Garner,C Hawkes,P Renzullo,F Garland,D Ewart,P Giangrande,C Lee,Andrew N. Phillips,R Spooner,J Wilde,Mark Winter,AM Johnson,JI Lorenzo,M Schechter,Collaborative Grp Aids Incubation +95 more
TL;DR: Before widespread use of highly-active antiretroviral therapy (before 1996), time since seroconversion and age at serconversion were the major determinants of survival and development of AIDS in Europe, North America, and Australia.
Journal ArticleDOI
Changes in the risk of death after HIV seroconversion compared with mortality in the general population.
Krishnan Bhaskaran,Osamah Hamouda,Mette Sannes,Faroudy Boufassa,Anne M Johnson,Paul C. Lambert,Kholoud Porter +6 more
TL;DR: In industrialized countries, persons infected sexually with HIV now appear to experience mortality rates similar to those of the general population in the first 5 years following infection, though a mortality excess remains as duration of HIV infection lengthens.
Journal ArticleDOI
HIV controllers: a homogeneous group of HIV-1-infected patients with spontaneous control of viral replication.
Olivier Lambotte,Faroudy Boufassa,Yoann Madec,Ahn Nguyen,Cécile Goujard,Laurence Meyer,Christine Rouzioux,Alain Venet,Jean-François Delfraissy +8 more
TL;DR: 15 patients who have maintained undetectable plasma HIV RNA loads without antiretroviral treatment for >10 years are identified, characterized by a low HIV DNA load in peripheral blood mononuclear cells and by a strong HIV-specific immune response.