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Fazlul H. Sarkar

Researcher at Wayne State University

Publications -  626
Citations -  48133

Fazlul H. Sarkar is an academic researcher from Wayne State University. The author has contributed to research in topics: Cancer & Pancreatic cancer. The author has an hindex of 114, co-authored 625 publications receiving 44744 citations.

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Inhibition Of Cell Growth And Induction Of Apoptosis In Non-Small Cell Lung Cancer Cells By Delta-Tocotrienol Is Associated With Notch-1 Down-Regulation

TL;DR: The results suggest that down‐regulation of Notch‐1, via inhibition of NF‐κB signaling pathways by delta‐tocotrienol, could provide a potential novel approach for prevention of tumor progression in non‐small cell lung cancer.
Journal Article

Genistein Potentiates the Radiation Effect on Prostate Carcinoma Cells

TL;DR: Genistein can augment the effect of neutrons at doses approximately 2-fold lower than photon doses required to observe the same efficacy, suggesting a potential of combining genistein with radiation for the treatment of localized prostate carcinoma.
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Tumor cell-mediated neovascularization and lymphangiogenesis contrive tumor progression and cancer metastasis.

TL;DR: Dual targeting of endothelial sprouting angiogenesis and tumor cell-mediated neovascularization and lymphangiogenesis may overcome current clinical problems with anti-angiogenic therapy, resulting in significantly improved anti-angelogenesis and anti-cancer therapies.
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Cyclooxygenase-2-dependent and -independent effects of celecoxib in pancreatic cancer cell lines

TL;DR: It is concluded that celecoxib potentiates gemcitabine-induced growth inhibition and apoptosis in pancreatic cell lines and down-regulation of transcription of the COX-2 enzyme is observed.
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Apoptosis‐inducing effect of garcinol is mediated by NF‐κB signaling in breast cancer cells

TL;DR: The first report on anti‐proliferative and apoptosis‐inducing action of garcinol against human breast cancer cells is reported and the results suggest that this natural compound merits investigation as a potential chemo‐preventive/‐therapeutic agent, especially against breast cancer.