F
Fazlul H. Sarkar
Researcher at Wayne State University
Publications - 626
Citations - 48133
Fazlul H. Sarkar is an academic researcher from Wayne State University. The author has contributed to research in topics: Cancer & Pancreatic cancer. The author has an hindex of 114, co-authored 625 publications receiving 44744 citations.
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In vitro and in vivo molecular evidence of genistein action in augmenting the efficacy of cisplatin in pancreatic cancer.
Sanjeev Banerjee,Yuxiang Zhang,Zhiwei Wang,Mingxin Che,Paul J. Chiao,James L. Abbruzzese,Fazlul H. Sarkar +6 more
TL;DR: This article has been retracted at the request of the editor‐in‐chief and author because of a lack of original research.
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Parenterally administrable nano-micelles of 3,4-difluorobenzylidene curcumin for treating pancreatic cancer.
TL;DR: Self-assembling nano-micelles of amphiphilic styrene-maleic acid copolymer with 3,4-Difluorobenzylidene curcumin (CDF) are engineered to be a versatile carrier for dose escalation and targeted delivery of CDF, with enhanced therapeutic margin and safety.
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Genistein Down-Regulates miR-223 Expression in Pancreatic Cancer Cells
Jia Ma,Long Cheng,Hao Liu,Jing Zhang,Ying Shi,Fanpeng Zeng,Lucio Miele,Fazlul H. Sarkar,Jun Xia,Zhiwei Wang +9 more
TL;DR: Genistein exerts its anti-tumor activity partly through downregulation of miR-223 in PC cells, suggesting that targeting miRNAs could be a novel strategy to treat human cancers.
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Suppression of human prostate cancer cell growth by ciprofloxacin is associated with cell cycle arrest and apoptosis
Olivia Aranha,Robert Grignon,Neelesh Fernandes,Timothy J. McDonnell,David P. Wood,Fazlul H. Sarkar +5 more
TL;DR: The results suggest the potential usefulness of the fluroquinolone, ciprofloxacin as a chemotherapeutic agent for advanced prostate cancer and show anti-proliferative and apoptosis inducing activity on prostate cancer cells but not on non-tumorigenic prostate epithelial cells.
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Inhibition of prostate specific antigen expression by genistein in prostate cancer cells.
TL;DR: Genistein inhibits cell growth similarly in both the LNCaP and VeCaP cell lines, but has differential effects on PSA expression, providing further evidence to support the role of genistein as a chemopreventive/therapeutic agent for prostate cancer irrespective of androgen responsiveness.