F
Fazlul H. Sarkar
Researcher at Wayne State University
Publications - 626
Citations - 48133
Fazlul H. Sarkar is an academic researcher from Wayne State University. The author has contributed to research in topics: Cancer & Pancreatic cancer. The author has an hindex of 114, co-authored 625 publications receiving 44744 citations.
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Journal ArticleDOI
Mechanisms of curcumin- and EGF-receptor related protein (ERRP)-dependent growth inhibition of colon cancer cells.
TL;DR: It is observed that the cell growth inhibition and stimulation of apoptosis in response to the combinatorial treatment was significantly greater than that caused by either agent alone.
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Resveratrol-Induced Apoptosis is enhanced in low pH environments associated with cancer
Uzma Shamim,Sarmad Hanif,Abdulmajeed Albanyan,Frances W.J. Beck,Bin Bao,Zhiwei Wang,Sanjeev Banerjee,Fazlul H. Sarkar,Ramzi M. Mohammad,S.M. Hadi,Asfar S. Azmi +10 more
TL;DR: The results reveal that growth inhibition and internucleosomal DNA fragmentation induced apoptosis in Capan‐2 and Panc‐28 pancreatic cancer cell lines is enhanced at lower pH, providing irrevocable proof that low pH environment can be turned into tumor weakness and assist in eradication of cancer cells by resveratrol.
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Clinicopathologic analysis of pancreatic adenocarcinoma in African Americans and Caucasians.
Nat L. Pernick,Fazlul H. Sarkar,Philip A. Philip,Patricia Arlauskas,Anthony F. Shields,Vainutis K. Vaitkevicius,Michael C. Dugan,N. Volkan Adsay +7 more
TL;DR: Although African American and Caucasian patients had similar survival rates associated with usual type pancreatic ductal adenocarcinoma, there were differences in management and expression of biologic markers between these two groups.
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Molecular Markers of Epithelial-to-Mesenchymal Transition Are Associated with Tumor Aggressiveness in Breast Carcinoma
Seema Sethi,Fazlul H. Sarkar,Quratulain Ahmed,Sudeshna Bandyopadhyay,Zeina Nahleh,Assaad Semaan,Wael Sakr,Adnan R. Munkarah,Rouba Ali-Fehmi +8 more
TL;DR: Vimentin, EGFR, and NF-κ B were significantly increased in triple-negative tumors, which is consistent with the aggressiveness of these tumors.
Journal Article
Induction of apoptosis and inhibition of c-erbB-2 in breast cancer cells by flavopiridol.
TL;DR: It is concluded that flavopiridol inhibits the growth of MDA-MB-435 breast cancer cells, induces apoptosis, regulates the expression of genes, and inhibits invasion and, thus, may inhibit metastasis of Breast cancer cells.