F
Fei Guan
Researcher at Rutgers University
Publications - 11
Citations - 800
Fei Guan is an academic researcher from Rutgers University. The author has contributed to research in topics: Cancer & Polyadenylation. The author has an hindex of 10, co-authored 11 publications receiving 736 citations. Previous affiliations of Fei Guan include Johnson & Johnson.
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Journal ArticleDOI
Cancer prevention by tea: Evidence from laboratory studies.
TL;DR: The cancer preventive activities of tea (Camellia sinensis Theaceae) have been studied extensively and the molecular mechanisms of inhibition of carcinogenesis in animals and humans remain to be further investigated.
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Pro-oxidative activities and dose–response relationship of (−)-epigallocatechin-3-gallate in the inhibition of lung cancer cell growth: a comparative study in vivo and in vitro
Guang Xun Li,Yu Kuo Chen,Zhe Hou,Hang Xiao,Huanyu Jin,Gary Lu,Mao Jung Lee,Ba Liu,Fei Guan,Zhihong Yang,Albert Yu,Chung S. Yang +11 more
TL;DR: Although E GCG is generally considered to be an antioxidant, the present study demonstrates the pro-oxidative activities of EGCG in vivo and in vitro in the described experimental system.
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Inhibiting expression of specific genes in mammalian cells with 5' end-mutated U1 small nuclear RNAs targeted to terminal exons of pre-mRNA.
Puri Fortes,Yolanda Cuevas,Fei Guan,Peng Liu,Sara Pentlicky,Stephen P. Jung,María L. Martínez-Chantar,Jesús Prieto,David W. Rowe,Samuel I. Gunderson +9 more
TL;DR: It is demonstrated that expression of endogenous mammalian genes can be efficiently inhibited by transiently or stably expressed 5′ end-mutated U1 snRNA, and a set of rules to use this technique and to improve the efficiency of inhibition are established.
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δ- and γ-Tocopherols, but not α-Tocopherol, Inhibit Colon Carcinogenesis in Azoxymethane-Treated F344 Rats
Fei Guan,Guangxun Li,Anna B. Liu,Mao-Jung Lee,Zhihong Yang,Yu-Kuo Chen,Yong Lin,Weichung Shih,Chung S. Yang +8 more
TL;DR: This study provides the first evidence for the much higher cancer preventive activity of δ-T and γ-T than α-T in a chemically induced colon carcinogenesis model and suggests that δ/T is more effective than γ/T.
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Cancer Prevention by Tocopherols and Tea Polyphenols
TL;DR: Data is presented showing that - and -tocopherols inhibit colon, lung, mammary and prostate carcinogenesis in animal models, whereas -ocopherol is ineffective in animal and human studies.