F
Fei Yang
Researcher at Johns Hopkins University School of Medicine
Publications - 33
Citations - 1274
Fei Yang is an academic researcher from Johns Hopkins University School of Medicine. The author has contributed to research in topics: Neuropathic pain & Stimulation. The author has an hindex of 17, co-authored 33 publications receiving 993 citations. Previous affiliations of Fei Yang include Howard Hughes Medical Institute & University of Virginia.
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Journal ArticleDOI
Cannabinoids suppress inflammatory and neuropathic pain by targeting α3 glycine receptors
Wei Xiong,Tanxing Cui,Kejun Cheng,Fei Yang,Shao Rui Chen,Dan Willenbring,Yun Guan,Hui Lin Pan,Ke Ren,Yan Xu,Li Zhang +10 more
TL;DR: Systemic and intrathecal administration of derivatives of a nonpsychoactive component of marijuana significantly suppresses chronic inflammatory and neuropathic pain, without causing analgesic tolerance, in several rodent models.
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Conventional and Kilohertz-frequency Spinal Cord Stimulation Produces Intensity- and Frequency-dependent Inhibition of Mechanical Hypersensitivity in a Rat Model of Neuropathic Pain
Ronen Shechter,Fei Yang,Qian Xu,Yong Kwan Cheong,Shao Qiu He,Andrei D. Sdrulla,Alene F. Carteret,Paul W. Wacnik,Xinzhong Dong,Richard A. Meyer,Srinivasa N. Raja,Yun Guan +11 more
TL;DR: Kilohertz SCS attenuated mechanical hypersensitivity in a time course and amplitude that differed from conventional 50 Hz SCS, and may involve different peripheral and spinal segmental mechanisms.
Journal ArticleDOI
Spinal cord stimulation-induced analgesia: electrical stimulation of dorsal column and dorsal roots attenuates dorsal horn neuronal excitability in neuropathic rats
Yun Guan,Paul W. Wacnik,Fei Yang,Alene F. Carteret,Chih yang Chung,Richard A. Meyer,Srinivasa N. Raja +6 more
TL;DR: stimulation of putative spinal substrates at A-fiber intensities with parameters similar to those used by patients with spinal cord stimulators attenuated established WDR neuronal hyperexcitability in the neuropathic condition and counteracted activity-dependent increase in neuronal excitability.
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Selective keratinocyte stimulation is sufficient to evoke nociception in mice
Zixuan Pang,Takashi Sakamoto,Vinod Tiwari,Yu Shin Kim,Fei Yang,Xinzhong Dong,Ali D. Güler,Yun Guan,Michael J. Caterina +8 more
TL;DR: It is found that keratinocyte stimulation was sufficient to induce strong expression of the neuronal activation marker, c-fos, in laminae I and II of the ipsilateral spinal cord dorsal horn and to evoke acute paw-licking nocifensive behavior and conditioned place aversion.
Journal ArticleDOI
Electrical stimulation of low-threshold afferent fibers induces a prolonged synaptic depression in lamina II dorsal horn neurons to high-threshold afferent inputs in mice.
Andrei D. Sdrulla,Qian Xu,Shao Qiu He,Vinod Tiwari,Fei Yang,Chen Zhang,Chen Zhang,Bin Shu,Ronen Shechter,Srinivasa N. Raja,Yun Wang,Xinzhong Dong,Yun Guan +12 more
TL;DR: Findings show that activities in A&bgr;-fibers lead to frequency-dependent depression of synaptic transmission in SG neurons in response to peripheral noxious inputs, which is similar to that experienced by naive mice after SNL.