F
Fen Zhang
Researcher at The Chinese University of Hong Kong
Publications - 48
Citations - 3526
Fen Zhang is an academic researcher from The Chinese University of Hong Kong. The author has contributed to research in topics: Microbiome & Gut flora. The author has an hindex of 13, co-authored 35 publications receiving 1360 citations. Previous affiliations of Fen Zhang include Nanchang University.
Papers
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Journal ArticleDOI
Alterations in Gut Microbiota of Patients With COVID-19 During Time of Hospitalization.
Tao Zuo,Fen Zhang,Grace Lui,Yun Kit Yeoh,Amy Li,Hui Zhan,Yating Wan,Arthur C.K. Chung,Chun Pan Cheung,Nan Chen,Christopher K C Lai,Zigui Chen,Eugene Y.K. Tso,Kitty S. C. Fung,Veronica L. Chan,Lowell Ling,Gavin M. Joynt,David S.C. Hui,Francis K.L. Chan,Paul K.S. Chan,Siew C. Ng +20 more
TL;DR: Fecal microbiota alterations were associated with fecal levels of SARS-CoV-2 and COVID-19 severity, and strategies to alter the intestinal microbiota might reduce disease severity.
Journal ArticleDOI
Gut microbiota composition reflects disease severity and dysfunctional immune responses in patients with COVID-19.
Yun Kit Yeoh,Tao Zuo,Grace Lui,Fen Zhang,Qin Liu,Amy Li,Arthur C.K. Chung,Chun Pan Cheung,Eugene Y.K. Tso,Kitty S. C. Fung,Veronica L. Chan,Lowell Ling,Gavin M. Joynt,David S.C. Hui,Kai Ming Chow,Susanna So Shan Ng,Timothy Li,Rita W Y Ng,Terry Cheuk-Fung Yip,Grace Lai-Hung Wong,Francis K.L. Chan,Chun K. Wong,Paul K.S. Chan,Siew C. Ng +23 more
TL;DR: In this article, the authors investigated whether the gut microbiome is linked to disease severity in patients with COVID-19, and whether perturbations in microbiome composition, if any, resolve with clearance of the SARS-CoV-2 virus.
Journal ArticleDOI
Depicting SARS-CoV-2 faecal viral activity in association with gut microbiota composition in patients with COVID-19.
Tao Zuo,Qin Liu,Fen Zhang,Grace Lui,Eugene Y.K. Tso,Yun Kit Yeoh,Zigui Chen,Siaw Shi Boon,Francis K.L. Chan,Paul K.S. Chan,Siew C. Ng +10 more
TL;DR: Evidence is provided for active and prolonged ‘quiescent’ GI infection even in the absence of GI manifestations and after recovery from respiratory infection of SARS-CoV-2.
Journal ArticleDOI
Gut mucosal virome alterations in ulcerative colitis
Tao Zuo,Xiao-Juan Lu,Yu Zhang,Chun Pan Cheung,Siu Lam,Fen Zhang,Whitney Tang,Jessica Y.L. Ching,Risheng Zhao,Paul K.S. Chan,Joseph J.Y. Sung,Jun Yu,Francis K.L. Chan,Qian Cao,Qian Cao,Jianqiu Sheng,Siew C. Ng +16 more
TL;DR: It is demonstrated for the first time that UC is characterised by substantial alterations of the mucosa virobiota with functional distortion, and multiple viral functions, particularly functions of bacteriophages associated with host bacteria fitness and pathogenicity were markedly enriched in UC mucosa.
Journal ArticleDOI
Alterations in Fecal Fungal Microbiome of Patients With COVID-19 During Time of Hospitalization until Discharge.
Tao Zuo,Hui Zhan,Fen Zhang,Qin Liu,Eugene Y.K. Tso,Grace Lui,Nan Chen,Amy Li,Wenqi Lu,Francis K.L. Chan,Paul K.S. Chan,Siew C. Ng +11 more
TL;DR: Heterogeneous configurations of the fecal mycobiome are found, with enrichment of fungal pathogens from the genera Candida and Aspergillus, during hospitalization of 30 patients with COVID-19 compared with controls.