Z
Zigui Chen
Researcher at The Chinese University of Hong Kong
Publications - 192
Citations - 10514
Zigui Chen is an academic researcher from The Chinese University of Hong Kong. The author has contributed to research in topics: Medicine & Population. The author has an hindex of 45, co-authored 164 publications receiving 7707 citations. Previous affiliations of Zigui Chen include South China Normal University & Albert Einstein College of Medicine.
Papers
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Journal ArticleDOI
Classification of Papillomaviruses (PVs) Based on 189 PV Types and Proposal of Taxonomic Amendments
Hans-Ulrich Bernard,Robert D. Burk,Zigui Chen,Koenraad Van Doorslaer,Harald zur Hausen,Ethel Michele De Villiers +5 more
TL;DR: It is discussed that based on emerging species concepts derived from genome sequences, PV types could be promoted to the taxonomic level of species, but it is not recommended to implement this change at the current time.
Journal ArticleDOI
Alterations in Gut Microbiota of Patients With COVID-19 During Time of Hospitalization.
Tao Zuo,Fen Zhang,Grace Lui,Yun Kit Yeoh,Amy Li,Hui Zhan,Yating Wan,Arthur C.K. Chung,Chun Pan Cheung,Nan Chen,Christopher K C Lai,Zigui Chen,Eugene Y.K. Tso,Kitty S. C. Fung,Veronica L. Chan,Lowell Ling,Gavin M. Joynt,David S.C. Hui,Francis K.L. Chan,Paul K.S. Chan,Siew C. Ng +20 more
TL;DR: Fecal microbiota alterations were associated with fecal levels of SARS-CoV-2 and COVID-19 severity, and strategies to alter the intestinal microbiota might reduce disease severity.
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The carcinogenicity of human papillomavirus types reflects viral evolution
Mark Schiffman,Rolando Herrero,Rob DeSalle,Allan Hildesheim,Sholom Wacholder,Ana Cecilia Rodriguez,M C Bratti,Mark E. Sherman,Jorge Morales,Diego Guillén,Mario Alfaro,Martha Hutchinson,Thomas C. Wright,Diane Solomon,Zigui Chen,John Schussler,Philip E. Castle,Robert D. Burk +17 more
TL;DR: HPV16 was uniquely likely both to persist and to cause neoplastic progression when it persisted, making it a remarkably powerful human carcinogen that merits separate clinical consideration, and several clear clues and research directions are presented in the ongoing efforts to understand HPV carcinogenesis.
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Mucosal microbiome dysbiosis in gastric carcinogenesis
Olabisi Oluwabukola Coker,Zhenwei Dai,Yongzhan Nie,Guijun Zhao,Lei Cao,Geicho Nakatsu,William K.K. Wu,Sunny H. Wong,Zigui Chen,Joseph J.Y. Sung,Jun Yu +10 more
TL;DR: Differences in bacterial interactions across stages of gastric carcinogenesis are identified and significant enrichments and network centralities suggest potentially important roles of P. pneumosintes, S. exigua, P. stomatis, D. micra and S. anginosus in GC progression.
Journal ArticleDOI
Human papillomavirus genome variants.
TL;DR: These studies provide the basis to define the genetics of HPV pathogenesis and the use of multiple sequence alignments of complete viral genomes and phylogenetic analyses have begun to define variant lineages and sublineages using empirically defined differences.