A
Arthur C.K. Chung
Researcher at Hong Kong Baptist University
Publications - 60
Citations - 7403
Arthur C.K. Chung is an academic researcher from Hong Kong Baptist University. The author has contributed to research in topics: Fibrosis & Renal fibrosis. The author has an hindex of 34, co-authored 57 publications receiving 5551 citations. Previous affiliations of Arthur C.K. Chung include The Chinese University of Hong Kong.
Papers
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Journal ArticleDOI
Alterations in Gut Microbiota of Patients With COVID-19 During Time of Hospitalization.
Tao Zuo,Fen Zhang,Grace Lui,Yun Kit Yeoh,Amy Li,Hui Zhan,Yating Wan,Arthur C.K. Chung,Chun Pan Cheung,Nan Chen,Christopher K C Lai,Zigui Chen,Eugene Y.K. Tso,Kitty S. C. Fung,Veronica L. Chan,Lowell Ling,Gavin M. Joynt,David S.C. Hui,Francis K.L. Chan,Paul K.S. Chan,Siew C. Ng +20 more
TL;DR: Fecal microbiota alterations were associated with fecal levels of SARS-CoV-2 and COVID-19 severity, and strategies to alter the intestinal microbiota might reduce disease severity.
Journal ArticleDOI
Gut microbiota composition reflects disease severity and dysfunctional immune responses in patients with COVID-19.
Yun Kit Yeoh,Tao Zuo,Grace Lui,Fen Zhang,Qin Liu,Amy Li,Arthur C.K. Chung,Chun Pan Cheung,Eugene Y.K. Tso,Kitty S. C. Fung,Veronica L. Chan,Lowell Ling,Gavin M. Joynt,David S.C. Hui,Kai Ming Chow,Susanna So Shan Ng,Timothy Li,Rita W Y Ng,Terry Cheuk-Fung Yip,Grace Lai-Hung Wong,Francis K.L. Chan,Chun K. Wong,Paul K.S. Chan,Siew C. Ng +23 more
TL;DR: In this article, the authors investigated whether the gut microbiome is linked to disease severity in patients with COVID-19, and whether perturbations in microbiome composition, if any, resolve with clearance of the SARS-CoV-2 virus.
Journal ArticleDOI
TGF-β/Smad3 Signaling Promotes Renal Fibrosis by Inhibiting miR-29
Wei Qin,Arthur C.K. Chung,Xiao R. Huang,Xiao-Ming Meng,David S.C. Hui,Cheuk-Man Yu,Joseph J.Y. Sung,Hui Y. Lan +7 more
TL;DR: In this paper, using a microRNA microarray and real-time PCR, wild-type mice had reduced expression of miR-29 along with the development of progressive renal fibrosis in obstructive nephropathy.
Journal ArticleDOI
Smad3-Mediated Upregulation of miR-21 Promotes Renal Fibrosis
TL;DR: It is demonstrated that Smad3, but not Smad2, signaling increases expression of miR-21, which promotes renal fibrosis, and inhibition of mi R-21 may be a therapeutic approach to suppress renal fibrot.
Journal ArticleDOI
miR-192 Mediates TGF-β/Smad3-Driven Renal Fibrosis
TL;DR: In this article, microarray and real-time PCR results demonstrated a tight association between upregulation of miR-192 in the fibrotic kidney and activation of TGF-beta/Smad signaling.