F
Florian Groeber
Researcher at Fraunhofer Society
Publications - 25
Citations - 1204
Florian Groeber is an academic researcher from Fraunhofer Society. The author has contributed to research in topics: Human skin & Skin equivalent. The author has an hindex of 14, co-authored 25 publications receiving 1001 citations. Previous affiliations of Florian Groeber include University of Stuttgart.
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Journal ArticleDOI
Skin tissue engineering--in vivo and in vitro applications.
Florian Groeber,Monika Holeiter,Monika Holeiter,Martina Hampel,Svenja Hinderer,Svenja Hinderer,Katja Schenke-Layland,Katja Schenke-Layland +7 more
TL;DR: In this paper, a review summarizes the advances in in vivo and in vitro applications of tissue-engineered skin and highlights novel efforts in the design of complex disease-in-a-dish models for studies ranging from disease etiology to drug development.
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Development of a human three-dimensional organotypic skin-melanoma spheroid model for in vitro drug testing
H Vörsmann,Florian Groeber,Heike Walles,S Busch,Stefan Beissert,Henning Walczak,Dagmar Kulms,Dagmar Kulms +7 more
TL;DR: An organotypic human skin-melanoma model is established that will facilitate efforts to improve therapeutic outcomes for malignant melanoma by providing a platform for the investigation of cytotoxic treatments and tailored therapies in a more physiological setting.
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Bioreactors in tissue engineering - principles, applications and commercial constraints
TL;DR: The use of bioreactor systems for the expansion of clinically relevant cell types is addressed, and the generation of functional three‐dimensional tissue equivalents for musculoskeletal tissue engineering are discussed.
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A first vascularized skin equivalent as an alternative to animal experimentation.
Florian Groeber,Lisa Engelhardt,Julia Lange,Szymon Kurdyn,Freia F. Schmid,Christoph Rücker,Stephan Mielke,Heike Walles,Jan Hansmann +8 more
TL;DR: The here shown skin equivalent has the potential for skin grafting and represents a sophisticated in vitro model for dermatological research.
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Impedance Spectroscopy for the Non-Destructive Evaluation of In Vitro Epidermal Models
Florian Groeber,Lisa Engelhardt,Sebastian Egger,Hedwig Werthmann,Michael G. Monaghan,Heike Walles,Jan Hansmann +6 more
TL;DR: In conclusion, results indicate that impedance spectroscopy can be employed as a non-destructive complementary method to assess mild irritative effects, which is currently not possible.