J
Jan Hansmann
Researcher at Fraunhofer Society
Publications - 101
Citations - 1573
Jan Hansmann is an academic researcher from Fraunhofer Society. The author has contributed to research in topics: Mesenchymal stem cell & Tissue engineering. The author has an hindex of 18, co-authored 90 publications receiving 1207 citations. Previous affiliations of Jan Hansmann include University of Würzburg & University of Applied Sciences Würzburg-Schweinfurt.
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Journal ArticleDOI
State-of-the-art of 3D cultures (organs-on-a-chip) in safety testing and pathophysiology.
Natalie Alépée,Anthony Bahinski,Mardas Daneshian,Bart De Wever,Ellen Fritsche,Alan M. Goldberg,Jan Hansmann,Thomas Hartung,John W. Haycock,Helena T. Hogberg,Lisa Hoelting,Jens M. Kelm,Suzanne Kadereit,Emily A. McVey,Robert Landsiedel,Marcel Leist,Marc Lübberstedt,Fozia Noor,Christian Pellevoisin,Dirk Petersohn,Uwe Pfannenbecker,Kerstin Reisinger,Tzutzuy Ramirez,Barbara Rothen-Rutishauser,Monika Schäfer-Korting,Katrin Zeilinger,Marie Gabriele Zurich +26 more
TL;DR: This review summarizes the state of the art concerning commonalities of the different models and indicates a roadmap for the successful implementation of 3D models in routine screening.
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Generation and transplantation of an autologous vascularized bioartificial human tissue.
Heike Mertsching,Johanna Schanz,Volker Steger,Markus Schandar,Martin Schenk,Jan Hansmann,Iris Dally,Godehard Friedel,Thorsten Walles +8 more
TL;DR: The feasibility to bioengineer a human tissue with an innate vascularization has been shown in vitro and the clinical setting and may open the door for the clinical application of various sophisticated bioartificial tissue substitutes and organ replacements.
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Bioreactors in tissue engineering - principles, applications and commercial constraints
TL;DR: The use of bioreactor systems for the expansion of clinically relevant cell types is addressed, and the generation of functional three‐dimensional tissue equivalents for musculoskeletal tissue engineering are discussed.
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Vascularised human tissue models: A new approach for the refinement of biomedical research
TL;DR: The biological vascularised scaffold (BioVaSc) is developed, which is the prerequisite for the generation of bioartificial tissues endued with a functional artificial vascular network and has been realized in artificial human liver-, intestine-, trachea- and skin-models.
Journal ArticleDOI
A first vascularized skin equivalent as an alternative to animal experimentation.
Florian Groeber,Lisa Engelhardt,Julia Lange,Szymon Kurdyn,Freia F. Schmid,Christoph Rücker,Stephan Mielke,Heike Walles,Jan Hansmann +8 more
TL;DR: The here shown skin equivalent has the potential for skin grafting and represents a sophisticated in vitro model for dermatological research.