F
Francesca Vulcano
Researcher at Istituto Superiore di Sanità
Publications - 27
Citations - 544
Francesca Vulcano is an academic researcher from Istituto Superiore di Sanità. The author has contributed to research in topics: Rhabdomyosarcoma & Medicine. The author has an hindex of 8, co-authored 20 publications receiving 473 citations.
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Journal ArticleDOI
Different ploidy levels of megakaryocytes generated from peripheral or cord blood CD34+ cells are correlated with different levels of platelet release.
Gianfranco Mattia,Francesca Vulcano,Luisa Milazzo,Alessandra Barca,Giampiero Macioce,Adele Giampaolo,H. Jane Hassan +6 more
TL;DR: The data indicate the inability of the CB-MKs to progress in the endomitotic process and a direct correlation between DNA content and platelet production.
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Key role of MEK/ERK pathway in sustaining tumorigenicity and in vitro radioresistance of embryonal rhabdomyosarcoma stem-like cell population
Carmela Ciccarelli,Francesca Vulcano,Luisa Milazzo,Giovanni Luca Gravina,Francesco Marampon,Giampiero Macioce,Adele Giampaolo,Vincenzo Tombolini,Virginia Di Paolo,Hamisa Jane Hassan,Bianca M. Zani +10 more
TL;DR: The results indicate that the MEK/ERK pathway plays a prominent role in maintaining the stem-like phenotype of RD cells, their survival and their innate radioresistance, thereby providing a promising therapy for embryonal rhabdomyosarcoma.
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Residual risk of transfusion-transmitted human immunodeficiency virus, hepatitis C virus, and hepatitis B virus infections in Italy.
Margarita Gonzalez,Vincenza Regine,Vanessa Piccinini,Francesca Vulcano,Adele Giampaolo,Hamisa Jane Hassan +5 more
TL;DR: The residual risk of TTI was estimated for nearly 90 percent of the blood supply in Italy and the risk of transfusion‐transmitted infections (TTIs) is essential for monitoring blood safety.
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Long–term platelet production assessed in NOD/SCID mice injected with cord blood CD34+ cells, thrombopoietin–amplified in clinical grade serum–free culture
Gianfranco Mattia,Luisa Milazzo,Francesca Vulcano,Massimiliano Pascuccio,Giampiero Macioce,Hamisa Jane Hassan,Adele Giampaolo +6 more
TL;DR: Platelet number obtained is within the minimum level considered sufficient for hemostasis, and amplified cells maintain their self-renewal capacity and multilineage potential differentiation, and transplantation of TPO-expanded CB cells has the potential favoring both platelet recovery and human engraftment.
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Wharton's jelly mesenchymal stromal cells have contrasting effects on proliferation and phenotype of cancer stem cells from different subtypes of lung cancer.
Francesca Vulcano,Luisa Milazzo,Carmela Ciccarelli,Adriana Eramo,Giovanni Sette,Annunziata Mauro,Giampiero Macioce,Andrea Martinelli,Renato Torre,Patrizia Casalbore,Hamisa Jane Hassan,Adele Giampaolo +11 more
TL;DR: It is suggested that WJMSC exert, both in vitro and in vivo, contrasting effects on LCSC derived from different lung tumor subtypes, with larger tumors than AC-LCSC alone.