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Francesca Vulcano

Researcher at Istituto Superiore di Sanità

Publications -  27
Citations -  544

Francesca Vulcano is an academic researcher from Istituto Superiore di Sanità. The author has contributed to research in topics: Rhabdomyosarcoma & Medicine. The author has an hindex of 8, co-authored 20 publications receiving 473 citations.

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Different ploidy levels of megakaryocytes generated from peripheral or cord blood CD34+ cells are correlated with different levels of platelet release.

TL;DR: The data indicate the inability of the CB-MKs to progress in the endomitotic process and a direct correlation between DNA content and platelet production.
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Key role of MEK/ERK pathway in sustaining tumorigenicity and in vitro radioresistance of embryonal rhabdomyosarcoma stem-like cell population

TL;DR: The results indicate that the MEK/ERK pathway plays a prominent role in maintaining the stem-like phenotype of RD cells, their survival and their innate radioresistance, thereby providing a promising therapy for embryonal rhabdomyosarcoma.
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Residual risk of transfusion-transmitted human immunodeficiency virus, hepatitis C virus, and hepatitis B virus infections in Italy.

TL;DR: The residual risk of TTI was estimated for nearly 90 percent of the blood supply in Italy and the risk of transfusion‐transmitted infections (TTIs) is essential for monitoring blood safety.
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Long–term platelet production assessed in NOD/SCID mice injected with cord blood CD34+ cells, thrombopoietin–amplified in clinical grade serum–free culture

TL;DR: Platelet number obtained is within the minimum level considered sufficient for hemostasis, and amplified cells maintain their self-renewal capacity and multilineage potential differentiation, and transplantation of TPO-expanded CB cells has the potential favoring both platelet recovery and human engraftment.