M
Maurilio Sampaolesi
Researcher at Katholieke Universiteit Leuven
Publications - 207
Citations - 11644
Maurilio Sampaolesi is an academic researcher from Katholieke Universiteit Leuven. The author has contributed to research in topics: Stem cell & Skeletal muscle. The author has an hindex of 44, co-authored 186 publications receiving 10533 citations. Previous affiliations of Maurilio Sampaolesi include University of Rome Tor Vergata & Seattle Children's Research Institute.
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Journal ArticleDOI
Tie2 identifies a hematopoietic lineage of proangiogenic monocytes required for tumor vessel formation and a mesenchymal population of pericyte progenitors.
Michele De Palma,Mary Anna Venneri,Rossella Galli,Lucia Sergi Sergi,Letterio S. Politi,Maurilio Sampaolesi,Luigi Naldini +6 more
TL;DR: It is demonstrated that monocytes expressing the Tie2 receptor (Tie2-expressing monocytes [TEMs]) are a distinct hematopoietic lineage of proangiogenic cells that are selectively recruited to spontaneous and orthotopic tumors and promote angiogenesis in a paracrine manner.
Journal ArticleDOI
Pericytes of human skeletal muscle are myogenic precursors distinct from satellite cells.
Arianna Dellavalle,Maurilio Sampaolesi,Rossana Tonlorenzi,Enrico Tagliafico,Benedetto Sacchetti,Laura Perani,Anna Innocenzi,Beatriz G. Gálvez,Graziella Messina,Roberta Morosetti,Sheng Li,Marzia Belicchi,Giuseppe M. Peretti,Jeffrey S. Chamberlain,Woodring E. Wright,Yvan Torrente,Stefano Ferrari,Paolo Bianco,Giulio Cossu +18 more
TL;DR: Data show that myogenic precursors, distinct from satellite cells, are associated with microvascular walls in the human skeletal muscle, may represent a correlate of embryonic 'mesoangioblasts' present after birth and may be a promising candidate for future cell-therapy protocols in patients.
Journal ArticleDOI
Mesoangioblast stem cells ameliorate muscle function in dystrophic dogs.
Maurilio Sampaolesi,Stéphane Blot,Giuseppe D'Antona,Nicolas Granger,Rossana Tonlorenzi,Anna Innocenzi,Paolo Mognol,Jean-Laurent Thibaud,Beatriz G. Gálvez,Inès Barthélémy,Laura Perani,Sara Mantero,Maria Guttinger,Orietta Pansarasa,Chiara Rinaldi,M. Gabriella Cusella De Angelis,Yvan Torrente,Claudio Bordignon,Roberto Bottinelli,Giulio Cossu +19 more
TL;DR: It is reported that intra-arterial delivery of wild-type canine mesoangioblasts (vessel-associated stem cells) results in an extensive recovery of dystrophin expression, normal muscle morphology and function, and a remarkable clinical amelioration and preservation of active motility.
Journal ArticleDOI
Cell Therapy of α-Sarcoglycan Null Dystrophic Mice Through Intra-Arterial Delivery of Mesoangioblasts
Maurilio Sampaolesi,Yvan Torrente,Anna Innocenzi,Rossana Tonlorenzi,Giuseppe D'Antona,M. Antonietta Pellegrino,Rita Barresi,Nereo Bresolin,M. Gabriella Cusella De Angelis,Kevin P. Campbell,Roberto Bottinelli,Giulio Cossu +11 more
TL;DR: In this paper, the authors used wild-type mesoangioblasts, a class of vessel-associated stem cells, to correct morphologically and functionally the dystrophic phenotype of virtually all downstream muscles in adult immunocompetent α-sarcoglycan null mice.
Journal ArticleDOI
Human postnatal dental pulp cells co-differentiate into osteoblasts and endotheliocytes: a pivotal synergy leading to adult bone tissue formation.
R D'Aquino,Antonio Graziano,Maurilio Sampaolesi,Gregorio Laino,Giuseppe Pirozzi,A. De Rosa,Gianpaolo Papaccio +6 more
TL;DR: This study provides direct evidence to suggest that osteogenesis and angiogenesis mediated by human SBP-DPSCs may be regulated by distinct mechanisms, leading to the organization of adult bone tissue after stem cell transplantion.