F
Francesco Dell'Accio
Researcher at Queen Mary University of London
Publications - 122
Citations - 6889
Francesco Dell'Accio is an academic researcher from Queen Mary University of London. The author has contributed to research in topics: Cartilage & Chondrocyte. The author has an hindex of 34, co-authored 105 publications receiving 6209 citations. Previous affiliations of Francesco Dell'Accio include Katholieke Universiteit Leuven & University of Bari.
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Multipotent mesenchymal stem cells from adult human synovial membrane
TL;DR: It is demonstrated that human multipotent MSCs can be isolated from the SM of knee joints and have the ability to proliferate extensively in culture, and they maintain their multilineage differentiation potential in vitro, establishing their progenitor cell nature.
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Skeletal muscle repair by adult human mesenchymal stem cells from synovial membrane
Cosimo De Bari,Francesco Dell'Accio,Frank Vandenabeele,Joris Vermeesch,Jean-Marc Raymackers,Frank P. Luyten +5 more
TL;DR: Adult human synovial membrane-derived mesenchymal stem cells (hSM-MSCs) have myogenic differentiation in a nude mouse model of skeletal muscle regeneration and proof of principle of their potential use for muscle repair in the mdx mice model of Duchenne muscular dystrophy is provided.
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Mesenchymal multipotency of adult human periosteal cells demonstrated by single‐cell lineage analysis
Cosimo De Bari,Francesco Dell'Accio,Johan Vanlauwe,Jeroen Eyckmans,Ilyas M. Khan,Charles W. Archer,Elena Jones,Dennis McGonagle,Thimios A. Mitsiadis,Costantino Pitzalis,Frank P. Luyten +10 more
TL;DR: It is demonstrated that, regardless of donor age, the adult human periosteum contains cells that, upon enzymatic release and culture expansion, are multipotent MSCs at the single-cell level.
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Human periosteum‐derived cells maintain phenotypic stability and chondrogenic potential throughout expansion regardless of donor age
TL;DR: Human PDCs are easily accessible, expandable, and maintain their chondrogenic potential, and are therefore promising progenitor cells for use in the repair of joint surface defects.
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Molecular markers predictive of the capacity of expanded human articular chondrocytes to form stable cartilage in vivo
TL;DR: Adult human articular chondrocytes have a finite capacity to form stable cartilage in vivo; this capacity is lost throughout passaging and can be monitored using a nude mouse model and associated molecular markers.