F
Francis A. Ennis
Researcher at University of Massachusetts Medical School
Publications - 249
Citations - 20940
Francis A. Ennis is an academic researcher from University of Massachusetts Medical School. The author has contributed to research in topics: Virus & Dengue virus. The author has an hindex of 76, co-authored 249 publications receiving 20083 citations. Previous affiliations of Francis A. Ennis include University of Massachusetts Amherst & Georgia State University.
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Journal ArticleDOI
Dengue Viremia Titer, Antibody Response Pattern, and Virus Serotype Correlate with Disease Severity
David W. Vaughn,Sharone Green,Siripen Kalayanarooj,Bruce L. Innis,Suchitra Nimmannitya,Saroj Suntayakorn,Timothy P. Endy,Boonyos Raengsakulrach,Alan L. Rothman,Francis A. Ennis,Ananda Nisalak +10 more
TL;DR: Higher peak titers were associated with increased disease severity for the 31 patients with a peak titer identified, and increased dengue disease severity correlated with high viremia titer, secondary d Dengue virus infection, and DEN-2 virus type.
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High circulating levels of the dengue virus nonstructural protein NS1 early in dengue illness correlate with the development of dengue hemorrhagic fever
Daniel H. Libraty,Paul R. Young,Darren Pickering,Timothy P. Endy,Siripen Kalayanarooj,Sharone Green,David W. Vaughn,Ananda Nisalak,Francis A. Ennis,Alan L. Rothman +9 more
TL;DR: In this paper, the secreted dengue virus nonstructural protein NS1 (sNS1) was measured daily in 32 children with Dengue-2 virus infections participating in a prospective, hospital-based study.
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Early Clinical and Laboratory Indicators of Acute Dengue Illness
Siripen Kalayanarooj,David W. Vaughn,S. Nimmannitya,Sharone Green,Saroj Suntayakorn,N. Kunentrasai,W. Viramitrachai,S. Ratanachu-eke,S. Kiatpolpoj,Bruce L. Innis,Alan L. Rothman,A. Nisalak,Francis A. Ennis +12 more
TL;DR: Simple clinical and laboratory parameters are identified that help to identify children with DF or DHF, including plasma AST levels were higher in children who developed DHF than in those with DF.
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Differing Influences of Virus Burden and Immune Activation on Disease Severity in Secondary Dengue-3 Virus Infections
Daniel H. Libraty,Timothy P. Endy,Huo-Shu H. Houng,Sharone Green,Siripen Kalayanarooj,Saroj Suntayakorn,Wanya Chansiriwongs,David W. Vaughn,Ananda Nisalak,Francis A. Ennis,Alan L. Rothman +10 more
TL;DR: Quantitative differences in virus burden and host immune responses, and the timing of type 1 cytokine responses, have differing influences on the severity of disease manifestations during secondary dengue-3 virus infections.
Journal ArticleDOI
Antibody-enhanced infection by HIV-1 via Fc receptor-mediated entry.
TL;DR: It is suggested that this immunological response to HIV-1, instead of protecting the host, potentially facilitates the infection and is compatible with the concept of FcR-mediated infection enhancement.