Francisco Navarro

TL;DR: A novel inhibitory MHC class I receptor of the immunoglobulin-superfamily is characterized, expressed not only by subsets of NK and T cells, but also by B cells, monocytes, macrophages, and dendritic cells, suggesting that diverse leukocyte lineages have adopted recognition of self–MHC class II molecules as a common strategy to control cellular activation during an immune response.

TL;DR: The results raise the possibility that CD94/NKG2‐mediated recognition of HLA‐E expressed on extravillous cytotrophoblasts plays an important role in maternal‐fetal cellular interactions.

TL;DR: It is demonstrated that NK recognition of cells expressing HLA‐G1 involves at least two non‐overlapping receptor‐ligand systems: the CD94/NKG2 interaction with HLA •E, and the engagement of the ILT2(LIR1) receptor by HLA•G1 molecules.

TL;DR: Data support the idea that the CD94/NKG2 receptor complex is involved in the recognition of cells expressing HLA-G1, and suggest that anti-HLA class I mAbs reconstituted their cytolytic activity comparably to anti- HLA class II mAbs.

TL;DR: A multigene family of immunoglobulin superfamily (Ig‐SF) killer cell inhibitory receptors (KIRs) specifically recognize HLA class I molecules, while the interaction with H‐2 products is mediated by members of the murine Ly49 C‐type lectin family.