Franco Borzio

TL;DR: In untreated patients with advanced HCC, female gender, clinical decompensation of cirrhosis, and multinodular tumor are independent prognostic predictors and should be taken into account for patient stratification in future therapeutic studies.

TL;DR: Resection could result in survival benefit over LRT for HCC patients regardless of their BCLC stage, provided that liver dysfunction (Child B or MELD>9) and PST>1 are absent.

TL;DR: The overall applicability of radical or effective HCC treatments was unaffected by old age, however, treatment distribution differed, elderly individuals being more frequently treated with percutaneous procedures and less frequently with resection or TACE.

TL;DR: Liver transplantation could result in survival benefit for patients with hepatocellular carcinoma and advanced liver cirrhosis and in those with intermediate tumours (BCLC stages B-C), regardless of the nodule number-size criteria.

TL;DR: Alpha‐fetoprotein serum levels have no prognostic meaning in well‐compensated cirrhosis patients with single, small HCC treated with curative intent.