F
Françoise Brignole-Baudouin
Researcher at Vision Institute
Publications - 117
Citations - 3982
Françoise Brignole-Baudouin is an academic researcher from Vision Institute. The author has contributed to research in topics: Medicine & Glaucoma. The author has an hindex of 31, co-authored 104 publications receiving 3308 citations. Previous affiliations of Françoise Brignole-Baudouin include Paris Descartes University & University of Burgundy.
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Journal ArticleDOI
Preservatives in eyedrops: The good, the bad and the ugly ☆
Christophe Baudouin,Antoine Labbé,Hong Liang,Aude Pauly,Aude Pauly,Aude Pauly,Françoise Brignole-Baudouin +6 more
TL;DR: Care should be taken to avoid the long-term use of preservatives, otherwise a less toxic alternative to BAK should be developed, as this weakly allergenic but highly toxic compound exerts dose- and time-dependent effects.
Journal ArticleDOI
The Ocular Surface of Glaucoma Patients Treated over the Long Term Expresses Inflammatory Markers Related to Both T-Helper 1 and T-Helper 2 Pathways
Christophe Baudouin,Hong Liang,Pascale Hamard,Luisa Riancho,Catherine Creuzot-Garcher,Jean-Michel Warnet,Jean-Michel Warnet,Françoise Brignole-Baudouin,Françoise Brignole-Baudouin +8 more
TL;DR: This study demonstrates the overexpression of 2 chemokine receptors in the conjunctival epithelium of glaucoma patients treated over the long term, suggesting that the chronic use of topical treatments may stimulate both the Th1 and Th2 systems simultaneously.
Journal ArticleDOI
Switching from a preserved to a preservative‐free prostaglandin preparation in topical glaucoma medication
Hannu Uusitalo,Enping Chen,Norbert Pfeiffer,Françoise Brignole-Baudouin,Kai Kaarniranta,Markku Leino,Päivi Puska,Elina Palmgren,Thomas Hamacher,Günter Hofmann,Gernot Petzold,Ulrich Richter,Tobias Riedel,Martin Winter,Auli Ropo +14 more
TL;DR: The tolerability and intraocular pressure (IOP) reducing effect of the first preservative‐free prostaglandin tafluprost (Taflotan®) in patients exhibiting ocular surface side‐effects during latanoprost (Xalatan®) treatment was investigated.
Journal ArticleDOI
Comparison of Toxicological Profiles of Benzalkonium Chloride and Polyquaternium-1: An Experimental Study
Antoine Labbé,Aude Pauly,Hong Liang,Françoise Brignole-Baudouin,C. Martin,Jean-Michel Warnet,Christophe Baudouin +6 more
TL;DR: It is demonstrated in vivo that high doses of PQ-1 were much less toxic than BAC, and in vivo confocal microscopy and impression cytology are new promising experimental approaches to studying the rat corneoconjunctival surface, particularly in the field of ocular surface toxicity.
Journal ArticleDOI
Conjunctival and corneal reactions in rabbits following short- and repeated exposure to preservative-free tafluprost, commercially available latanoprost and 0.02% benzalkonium chloride.
TL;DR: It is confirmed that rabbit corneoconjunctival surfaces presented a better tolerance when treated with PF-tafluprost compared with commercially available latanoprost or BAK solution.