Pascale Hamard

TL;DR: Ex vivo and in vitro studies demonstrate that BAC-containing latanoprost and timolol exhibit higher proinflammatory and proapoptotic effects on conjunctival cells than does unpreserved Timolol, and suggest a potential protective effect of the prostaglandin analogue and to a lesser extent of timlol against the toxicity of BAC in conjunctivals.

TL;DR: The present study confirms the increased expression of immunoinflammatory markers by the conjunctival epithelium of glaucoma patients treated over the long term and the development of nontoxic preservatives or preservative-free solutions is therefore of great interest.

TL;DR: This study demonstrates the overexpression of 2 chemokine receptors in the conjunctival epithelium of glaucoma patients treated over the long term, suggesting that the chronic use of topical treatments may stimulate both the Th1 and Th2 systems simultaneously.

TL;DR: By providing details of the structures of filtering blebs at the cellular level, in vivo confocal microscopy constitutes a new promising way to understand wound healing mechanisms after filtering surgery.

TL;DR: At concentrations higher than those supposed to be found in the aqueous humor after instillation (1/100 dilution), unpreserved beta-blocker exhibited no proapoptotic activity on HTM cells in vitro.