F
Frank Baganz
Researcher at University of Manchester
Publications - 4
Citations - 1352
Frank Baganz is an academic researcher from University of Manchester. The author has contributed to research in topics: Saccharomyces cerevisiae & Gene. The author has an hindex of 4, co-authored 4 publications receiving 1268 citations.
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Journal ArticleDOI
Systematic functional analysis of the yeast genome
TL;DR: The genome sequence of the yeast Saccharomyces cerevisiae has provided the first complete inventory of the working parts of a eukaryotic cell, and systematic and comprehensive approaches to the elucidation of yeast gene function are discussed.
Journal ArticleDOI
Suitability of replacement markers for functional analysis studies in Saccharomyces cerevisiae.
TL;DR: It is demonstrated that HO is a selectively neutral site for gene replacement, but there is a significant marker effect associated with HIS3 which is dependent on the physiological conditions used for the competition experiments, and nutritional markers should not be used to generate deletion mutants for quantitative analysis of gene function in yeast.
Journal ArticleDOI
Quantitative analysis of yeast gene function using competition experiments in continuous culture.
Frank Baganz,Andrew Hayes,Ronnie Farquhar,Philip R. Butler,David C. J. Gardner,Stephen G. Oliver +5 more
TL;DR: It is shown that both densitometry and GeneScan™ analysis can be used with similar accuracy and reproducibility to determine the proportions of (at least) two strains simultaneously, in the range 10–90% of the total cell population.
Book ChapterDOI
Metabolic control analysis as a tool in the elucidation of the function of novel genes
TL;DR: The chapter explains the basic concepts and theorems of MCA with respect to its implications for the elucidation of the functions of novel genes and uses a simple kinetic model that mimics functional analysis experiments.