F
Frank Egan
Researcher at University College Cork
Publications - 6
Citations - 237
Frank Egan is an academic researcher from University College Cork. The author has contributed to research in topics: Gene & Transcriptome. The author has an hindex of 6, co-authored 6 publications receiving 200 citations.
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Journal ArticleDOI
Genomic analysis of the type VI secretion systems in Pseudomonas spp.: novel clusters and putative effectors uncovered
TL;DR: Using a combination of phylogenetic and meta-analysis of transcriptome datasets it was possible to associate specific subsets of VgrG and Hcp proteins with each Pseudomonas T6SS clade, and it is proposed that these genes may play a role in secretion or alternatively could be new T6S effectors.
Journal ArticleDOI
Distribution and diversity of bacterial secretion systems across metagenomic datasets
TL;DR: This analysis demonstrates that some secretion systems are over-represented in some specific samples and some T3SS and T6SS phylogenetic clusters were specifically enriched in particular ecological niches, which could indicate specific bacterial adaptation to these environments.
Book ChapterDOI
Exploiting New Systems-Based Strategies to Elucidate Plant–Bacterial Interactions in the Rhizosphere
Journal ArticleDOI
The SPI-1-like Type III secretion system: more roles than you think
TL;DR: The multiple roles of the SPI-1 T3SS are reviewed and it is discussed both how these discoveries are changing the perception of the SPI-1 family and what impacts this has on the understanding of the specialization of the T2SS in general.
Journal ArticleDOI
Characterization of the SPI‐1 and Rsp type three secretion systems in Pseudomonas fluorescens F113
Matthieu Barret,Frank Egan,Jennifer A. Moynihan,John P. Morrissey,Olivier Lesouhaitier,Fergal O'Gara +5 more
TL;DR: The genetic organization and expression of these two T3SS loci have been analysed by a combination of transcriptional reporter fusions and transcriptome analyses and revealed that the transcriptional activator hilA is induced by amoeba and that the SPI-1 T3 SS could potentially be involved in resistance to amoEBoid grazing.