F
Frank G. Ratcliff
Researcher at John Innes Centre
Publications - 5
Citations - 1765
Frank G. Ratcliff is an academic researcher from John Innes Centre. The author has contributed to research in topics: Gene & Gene silencing. The author has an hindex of 5, co-authored 5 publications receiving 1695 citations. Previous affiliations of Frank G. Ratcliff include French Alternative Energies and Atomic Energy Commission.
Papers
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Journal ArticleDOI
A similarity between viral defense and gene silencing in plants.
TL;DR: In this article, it was found that nepovirus infection of nontransgenic plants induces a resistance mechanism that is similar to transgene-induced gene silencing, which may be related to natural defense against viruses.
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Gene silencing without DNA. rna-mediated cross-protection between viruses
TL;DR: Analysis of plants infected with viruses that are quite distinct from the nepovirus or caulimovirus groups demonstrates that this RNA-mediated defense is a general response to virus infection, and provides direct evidence that post-transcriptional gene silencing of nuclear genes is a manifestation of a natural defense mechanism that is induced by a wide range of viruses.
Journal ArticleDOI
RNA-directed transcriptional gene silencing in plants can be inherited independently of the RNA trigger and requires Met1 for maintenance
TL;DR: Investigation of RNA-triggered events can lead to heritable changes in gene expression, and it is possible that initiation of other epigenetic phenomena such as trans-silencing and paramutation may have an RNA component.
Patent
Recombinant plant viral vectors
TL;DR: In this paper, nucleic acid vectors which include a transfer nucleotide sequence comprising a plant active promoter, operably linked to a recombinant tobacco rattle virus (TRV) cDNA (preferably derived from TRV RNA2) are described.
Journal ArticleDOI
Activation of osmotically-activated potassium transporters after injection of mRNA from A6 cells in Xenopus oocytes
Frank G. Ratcliff,J Ehrenfeld +1 more
TL;DR: The present study reports that the activation of hypo-osmotically-activated potassium transporters in the oocytes of Xenopus laevis differs quantitatively and in part qualitatively from the endogenous K+ pathways of non-inject and of water-injected Xenopus oocytes.