Frank Kloss

TL;DR: Low oxygen levels in this location provide a milieu that extends cellular lifespan and furthermore is instructive for the stemness of MSC allowing proliferation upon stimulation while suppressing differentiation, support the preliminary finding that primary MSC are enriched at the surface of spongy bone.

TL;DR: This paper provides a comprehensive overview of surface modifications that beneficially alter the topography, hydrophilicity, and outer coating of dental implants in order to enhance osseointegration in healthy as well as in compromised bone.

TL;DR: An overview of the principles of bone replacement, the types of graft materials available, and future perspectives are presented and a change from a simple replacement material to an individually created composite biomaterial with osteoinductive properties to enable enhanced defect bridging is proposed.

TL;DR: The results indicate that this surface modification method designed for sustained local release of Sr from implants may have applications within the orthopedic and dental industry.

TL;DR: It is demonstrated that coating of endosseous implants with nanocrystalline diamond (NCD) allows stable functionalization by means of physisorption with BMP-2, and this technical advancement can be readily applied in clinical therapies with regard to bone healing.