F
Frantz Rom Poulsen
Researcher at Odense University Hospital
Publications - 121
Citations - 2161
Frantz Rom Poulsen is an academic researcher from Odense University Hospital. The author has contributed to research in topics: Medicine & Population. The author has an hindex of 23, co-authored 90 publications receiving 1657 citations. Previous affiliations of Frantz Rom Poulsen include Odense University & University of Southern Denmark.
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Journal ArticleDOI
Organotypic hippocampal slice cultures for studies of brain damage, neuroprotection and neurorepair.
Jens Noraberg,Frantz Rom Poulsen,Morten Blaabjerg,Bjarne Winther Kristensen,Christian Bonde,Maria Montero,Morten Meyer,Jan Bert Gramsbergen,Jens Zimmer +8 more
TL;DR: Studies using hippocampal slice cultures to investigate mechanisms and treatment strategies for the neurodegenerative disorders like stroke, Alzheimer's disease, and epilepsia are summarized and reviewed.
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Modulator effects of interleukin-1beta and tumor necrosis factor-alpha on AMPA-induced excitotoxicity in mouse organotypic hippocampal slice cultures.
Liliana Bernardino,Sara Xapelli,Ana P. Silva,Birthe Jakobsen,Frantz Rom Poulsen,Catarina R. Oliveira,Annamaria Vezzani,João O. Malva,Jens Zimmer +8 more
TL;DR: It is demonstrated that the potentiation of AMPA-induced toxicity by TNF-α involves TNF receptor-1, whereas the neuroprotective effect is mediated by T NF receptor-2, relevant for understanding the role of proinflammatory cytokines and microglia activation in acute and chronic excitotoxic conditions.
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Association of Antithrombotic Drug Use With Subdural Hematoma Risk
David Gaist,Luis A. García Rodríguez,Maja Hellfritzsch,Frantz Rom Poulsen,Bo Halle,Jesper Hallas,Anton Pottegård +6 more
TL;DR: In Denmark, antithrombotic drug use was associated with higher risk of subdural hematoma and was highest when a VKA was used concurrently with an antiplatelet drug.
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Group I metabotropic glutamate receptors reduce excitotoxic injury and may facilitate neurogenesis
TL;DR: The data suggest that prolonged activation of group I mGluRs reduces nerve cell susceptibility to excitotoxic injury in a PLC-dependent manner; this reduction is associated with a P LC-dependent depression of excitatory synaptic transmission; and mGLUR1 activation may facilitate neurogenesis.
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Comparison of neuroprotective effects of erythropoietin (EPO) and carbamylerythropoietin (CEPO) against ischemia-like oxygen-glucose deprivation (OGD) and NMDA excitotoxicity in mouse hippocampal slice cultures
Maria Montero,Frantz Rom Poulsen,Jens Noraberg,Agnete Kirkeby,Johan van Beek,Marcel Leist,Marcel Leist,Jens Zimmer +7 more
TL;DR: CEPO is at least as efficient neuroprotectant as EPO when excitotoxicity is modeled in mouse hippocampal slice cultures, and both EPO and CEPO significantly reduced formation of spectrin cleavage products in the OGD model.