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Frédéric Charlotte

Researcher at University of Paris

Publications -  315
Citations -  27482

Frédéric Charlotte is an academic researcher from University of Paris. The author has contributed to research in topics: Liver biopsy & Histiocytosis. The author has an hindex of 75, co-authored 295 publications receiving 24972 citations. Previous affiliations of Frédéric Charlotte include Centre national de la recherche scientifique & Oregon Health & Science University.

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HHV-8-associated T-cell lymphoma in a lymph node with concurrent peritoneal effusion in an HIV-positive man.

TL;DR: A rare case of HHV-8-associated “solid PEL” of T-cell type in a 41-year-old HIV-seropositive man with a concomitant peritoneal effusion is reported.
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The histiocytosis Erdheim–Chester disease is an inflammatory myeloid neoplasm

TL;DR: Recurrent mutations of the MAPK and Pik3 pathways (NRAS, PIK3CA) have recently been described and should lead to a new classification of histiocytic disorders such that Langerhans cell Histiocytosis and ECD are classified as inflammatory myeloid neoplasms.
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Histological features predictive of liver fibrosis in chronic hepatitis C infection.

TL;DR: In this paper, the degree of liver fibrogenesis was evaluated by quantification of type I collagen mRNA and transforming growth factor (TGF) beta 1 mRNA (a major profibrogenic cytokine) in liver biopsy specimens from 28 patients with chronic hepatitis C and five controls, using a quantitative reverse transcription polymerase chain reaction (RT-PCR) assay.
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Fertile Homozygous Transgenic Mice Expressing a Functional Truncated Herpes Simplex Thymidine Kinase ΔTK Gene

TL;DR: A truncated TK variant not expressed in the testis is designed and generated to dramatically facilitate the development of transgenic mice expressing a conditional suicide gene.
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Distribution of Foxp3‐, CD4‐ and CD8‐positive lymphocytic cells in benign and malignant prostate tissue

TL;DR: The presence of Foxp3‐, CD4‐ and CD8‐positive lymphocytic cells in benign and malignant prostate tissue in APMIS 2010 indicates that these cells are important for the development of cancerous tumours.