Frédérique Brockly

TL;DR: A single-chain antibody fragment specific for human major histocompatibility complex class I molecules was shown to be able to redefine the tropism of ecotropic Moloney murine leukemia virus-derived retroviral particles by allowing infection of majorhistocompatible human cells.

TL;DR: Targeting the ROS/SUMO axis might constitute a therapeutic strategy for AML patients resistant to conventional chemotherapies.

TL;DR: Comparison of 60 human immunoglobulin variable lambda sequences allowed us to define seven subgroups designated VλI to VλVII, and it is demonstrated that all λ proteins sequenced so far fall into the subgroups I, II, III and VI, and that the λ regions previously assigned to sub groups IV and V belong, in fact, to subgroups III and II, respectively.

TL;DR: It is demonstrated that a unique Xho I fragment of 120 kilobases contains the fourteen TRGV genes and that the hybridization of that fragment in pulsed‐field gel electrophoresis (PFGE) allows linkage of the variable region to the constant region locus.

TL;DR: The data show that multiple degradation mechanisms, differing according to the conditions of expression, may operate on c-Fos to ensure a proper level and/or timing of expression and indicate that the half-life of c-fos during the G0/G1 phase transition is determined by a delicate balance between opposing stabilizing and destabilizing mechanisms operating at the same time.