P
Piona Dariavach
Researcher at Centre national de la recherche scientifique
Publications - 19
Citations - 1105
Piona Dariavach is an academic researcher from Centre national de la recherche scientifique. The author has contributed to research in topics: Syk & Gene. The author has an hindex of 12, co-authored 18 publications receiving 1056 citations. Previous affiliations of Piona Dariavach include Laboratory of Molecular Biology & University of Montpellier.
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Journal ArticleDOI
Human Ig superfamily CTLA-4 gene: chromosomal localization and identity of protein sequence between murine and human CTLA-4 cytoplasmic domains.
TL;DR: There is, remarkably, a complete identity of their cytoplasmic domains between the human and murine CTLA‐4 proteins and this complete interspecies conservation comes in support of an important role for this domain in CTla‐4 function.
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The B-cell antigen receptor of the five immunoglobulin classes
Ashok R. Venkitaraman,Gareth T. Williams,Piona Dariavach,Piona Dariavach,Michael S. Neuberger +4 more
TL;DR: It is shown that just two chains, the α and β associated chains, are sufficient to reconstitute an IgM surface receptor in fibroblasts and pro-pose that B-cell antigen receptors consist of a common α/β heterodimer associated with each immunoglobulin class.
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Variable region genes in the human T-cell rearranging gamma (TRG) locus: V-J junction and homology with the mouse genes.
TL;DR: Comparison of the V‐J junction and N region from transcripts or rearranged TRG genes belonging to the different subgroups shows no evidence of D segments in the human TRG locus, which brings the number of human V gamma genes whose sequence is known to 13 and reveals unexpected homology with the mouse V Gamma genes.
Journal ArticleDOI
Molecular mapping of the human T cell receptor gamma (TRG) genes and linkage of the variable and constant regions
Marie-Paule Lefranc,Paul Chuchana,Piona Dariavach,Catherine Nguyen,Sylvie Huck,Frédérique Brockly,Bertrand Jordan,Gérard Lefranc +7 more
TL;DR: It is demonstrated that a unique Xho I fragment of 120 kilobases contains the fourteen TRGV genes and that the hybridization of that fragment in pulsed‐field gel electrophoresis (PFGE) allows linkage of the variable region to the constant region locus.
Journal Article
Polymorphism of immunoglobulin lambda constant region genes in populations from France, Lebanon and Tunisia.
TL;DR: The decrease of the 8-kb fragment (allele A1) frequency and the increase of that of the 13-kb and 18-kb fragments (alleles A2 and A3) seemed to be correlated to a Negroid African contribution in the gene pool more important in Tunisia than in Lebanon.