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Fumihiko Kajiya
Researcher at Kawasaki Medical School
Publications - 229
Citations - 5441
Fumihiko Kajiya is an academic researcher from Kawasaki Medical School. The author has contributed to research in topics: Blood flow & Coronary circulation. The author has an hindex of 40, co-authored 229 publications receiving 5268 citations. Previous affiliations of Fumihiko Kajiya include Kawasaki University of Medical Welfare & Okayama University.
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Journal ArticleDOI
Effects of size and shape (aspect ratio) on the hemodynamics of saccular aneurysms: a possible index for surgical treatment of intracranial aneurysms.
Hiroshi Ujiie,Hiroyuki Tachibana,Osamu Hiramatsu,Andrew L. Hazel,Takeshi Matsumoto,Yasuo Ogasawara,Hiroshi Nakajima,Tomokatsu Hori,Kintomo Takakura,Fumihiko Kajiya +9 more
TL;DR: The localized, extremely low-flow condition that was observed in the dome of aneurysms with aspect ratios of more than 1.6 is a common flow characteristic in the geometry of ruptured aneuryms, so great care should be taken for patients with unruptured intracranial aneurYSms with approach to rupture.
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Role of hyaluronic acid glycosaminoglycans in shear-induced endothelium-derived nitric oxide release.
Seiichi Mochizuki,Hans Vink,Osamu Hiramatsu,Tatsuya Kajita,Fumiyuki Shigeto,Jos A. E. Spaan,Fumihiko Kajiya +6 more
TL;DR: In this article, the authors investigated the role of the endothelial cell glycocalyx as a biomechanical sensor for the synthesis of nitric oxide (NO) in response to chemical and physical stimuli.
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Endothelial dysfunction in ischemic acute renal failure: rescue by transplanted endothelial cells
Sergey V. Brodsky,Tokunori Yamamoto,Tetsuhiro Tada,Byungsoo Kim,Jun Chen,Fumihiko Kajiya,Michael S. Goligorsky +6 more
TL;DR: In an attempt to ameliorate the hemodynamic consequences of lost endothelial integrity, transplanted endothelial cells or surrogate cells expressing functional endothelial nitric oxide synthase into rats subjected to renal artery clamping resulted in a dramatic functional protection of ischemic kidneys.
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Intravital videomicroscopy of peritubular capillaries in renal ischemia
Tokunori Yamamoto,Tetsuhiro Tada,Sergey V. Brodsky,Hiroyoshi Tanaka,Eisei Noiri,Fumihiko Kajiya,Michael S. Goligorsky +6 more
TL;DR: It is suggested that a functional vasculopathy develops very early in the course of ischemia-reperfusion in superficial cortical microvasculature and is more pronounced in peritubular capillaries, thus accounting for the development of patchy injury of tubular epithelia.
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Hydrogen peroxide, an endogenous endothelium-derived hyperpolarizing factor, plays an important role in coronary autoregulation in vivo.
Toyotaka Yada,Hiroaki Shimokawa,Osamu Hiramatsu,Tatsuya Kajita,Fumiyuki Shigeto,Masami Goto,Yasuo Ogasawara,Fumihiko Kajiya +7 more
TL;DR: The results suggest that H2O2 is an endogenous EDHF in vivo and plays an important role in coronary autoregulation in cooperation with NO and adenosine.