G
Gabriel Rodrigo Fries
Researcher at University of Texas Health Science Center at Houston
Publications - 161
Citations - 5754
Gabriel Rodrigo Fries is an academic researcher from University of Texas Health Science Center at Houston. The author has contributed to research in topics: Bipolar disorder & Medicine. The author has an hindex of 37, co-authored 134 publications receiving 4612 citations. Previous affiliations of Gabriel Rodrigo Fries include Max Planck Society & University of Texas at Austin.
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Journal ArticleDOI
The role of inflammation and microglial activation in the pathophysiology of psychiatric disorders
Gislaine Z. Réus,Gislaine Z. Réus,Gabriel Rodrigo Fries,Laura Stertz,Marwa Badawy,Ives Cavalcante Passos,Tatiana Barichello,Flávio Kapczinski,João Quevedo +8 more
TL;DR: The role of inflammation in the pathophysiology of psychiatric disorders, such as MDD, BD, schizophrenia, and autism will be highlighted and the role of microglial activation and associated molecular cascades will be discussed as a means by which these neuroinflammatory mechanisms take place.
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Acute administration of ketamine induces antidepressant-like effects in the forced swimming test and increases BDNF levels in the rat hippocampus
Lêda Soares Brandão Garcia,Clarissa M. Comim,Samira S. Valvassori,Gislaine Z. Réus,Luciana M. Barbosa,Ana Cristina Andreazza,Laura Stertz,Gabriel Rodrigo Fries,Elaine C. Gavioli,Flávio Kapczinski,João Quevedo +10 more
TL;DR: The findings suggest that the increase of hippocampal BDNF protein levels induced by ketamine might be necessary to produce a rapid onset of antidepressant action.
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Brain-derived neurotrophic factor as a state-marker of mood episodes in bipolar disorders: A systematic review and meta-regression analysis
Brisa Simoes Fernandes,Clarissa Severino Gama,Keila Maria Mendes Ceresér,Lakshmi N. Yatham,Gabriel Rodrigo Fries,Gabriela D. Colpo,David Freitas de Lucena,Maurício Kunz,Fabiano Alves Gomes,Flávio Kapczinski +9 more
TL;DR: BDNF levels are consistently reduced during manic and depressive episodes and recover after treatment for acute mania, and data suggest that peripheral BDNF could be used as a biomarker of mood states and disease progression for BD.
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Peripheral biomarkers and illness activity in bipolar disorder.
Flávio Kapczinski,Felipe Dal-Pizzol,Antônio Lúcio Teixeira,Pedro Vieira da Silva Magalhães,Márcia Kauer-Sant'Anna,Fábio Klamt,José Cláudio Fonseca Moreira,Mateus Augusto de Bittencourt Pasquali,Gabriel Rodrigo Fries,João Quevedo,Clarissa Severino Gama,Robert M. Post +11 more
TL;DR: An en bloc assessment of a set of previously described biomarkers in different mood states as well as in healthy subjects, finding several of the markers discriminated between the bipolar and control groups, especially when patients were in acute episodes.
Journal ArticleDOI
Serum levels of IL-6, IL-10 and TNF-α in patients with bipolar disorder and schizophrenia: differences in pro- and anti-inflammatory balance
Maurício Kunz,Keila Maria Mendes Ceresér,Pedro Domingues Goi,Gabriel Rodrigo Fries,Antônio Lúcio Teixeira,Brisa Simoes Fernandes,Paulo Belmonte-de-Abreu,Márcia Kauer-Sant'Anna,Flávio Kapczinski,Clarissa Severino Gama +9 more
TL;DR: These findings evidence a chronic immune activation in schizophrenia, and increased anti-inflammatory factor IL-10 in bipolar disorder and schizophrenia suggests different patterns of inflammatory balance between these two disorders.