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Elaine C. Gavioli
Researcher at Federal University of Rio Grande do Norte
Publications - 99
Citations - 3298
Elaine C. Gavioli is an academic researcher from Federal University of Rio Grande do Norte. The author has contributed to research in topics: NOP & Nociceptin receptor. The author has an hindex of 27, co-authored 92 publications receiving 2931 citations. Previous affiliations of Elaine C. Gavioli include Universidade do Extremo Sul Catarinense & University of Ferrara.
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Journal ArticleDOI
Acute administration of ketamine induces antidepressant-like effects in the forced swimming test and increases BDNF levels in the rat hippocampus
Lêda Soares Brandão Garcia,Clarissa M. Comim,Samira S. Valvassori,Gislaine Z. Réus,Luciana M. Barbosa,Ana Cristina Andreazza,Laura Stertz,Gabriel Rodrigo Fries,Elaine C. Gavioli,Flávio Kapczinski,João Quevedo +10 more
TL;DR: The findings suggest that the increase of hippocampal BDNF protein levels induced by ketamine might be necessary to produce a rapid onset of antidepressant action.
Journal ArticleDOI
Effects of chronic mild stress on the oxidative parameters in the rat brain.
Giancarlo Lucca,Clarissa M. Comim,Samira S. Valvassori,Gislaine Z. Réus,Francieli Vuolo,Fabricia Petronilho,Felipe Dal-Pizzol,Elaine C. Gavioli,João Quevedo +8 more
TL;DR: The results support the idea that stress produces oxidants and an imbalance between superoxide dismutase and catalase activities that contributes to stress-related diseases, such as depression.
Journal ArticleDOI
Ketamine treatment reverses behavioral and physiological alterations induced by chronic mild stress in rats
Lêda Soares Brandão Garcia,Clarissa M. Comim,Samira S. Valvassori,Gislaine Z. Réus,Laura Stertz,Flávio Kapczinski,Elaine C. Gavioli,João Quevedo +7 more
TL;DR: These findings support the idea of a putative role of NMDA receptors in mood-related symptoms, and rapid and robust effects of ketamine in reverting mainly physiological alterations induced by chronic mild stressful situations in rats.
Journal ArticleDOI
Increased oxidative stress in submitochondrial particles into the brain of rats submitted to the chronic mild stress paradigm.
Giancarlo Lucca,Clarissa M. Comim,Samira S. Valvassori,Gislaine Z. Réus,Francieli Vuolo,Fabricia Petronilho,Elaine C. Gavioli,Felipe Dal-Pizzol,João Quevedo +8 more
TL;DR: Observations support the view that the CMS model of depression mimics alterations observed in depressed patients, and affords a useful system in which to test the hypothesis that altered brain energy metabolism is associated with neuropsychiatric disorders.
Journal ArticleDOI
Blockade of nociceptin/orphanin FQ-NOP receptor signalling produces antidepressant-like effects: pharmacological and genetic evidences from the mouse forced swimming test.
Elaine C. Gavioli,Giuliano Marzola,Remo Guerrini,Rosalia Bertorelli,Silvia Zucchini,T.C.M. De Lima,Giles A. Rae,S. Salvadori,Domenico Regoli,Girolamo Calo +9 more
TL;DR: Results indicate that blockade of the N/OFQ‐NOP receptor signalling in the brain produces antidepressant‐like effects in the mouse FST, and support the NOP receptor as a candidate target for the development of innovative antidepressant drugs.