G
Gabrielle E. Ahlzadeh
Researcher at University of Michigan
Publications - 3
Citations - 119
Gabrielle E. Ahlzadeh is an academic researcher from University of Michigan. The author has contributed to research in topics: Genetic enhancement & Pseudomonas exotoxin. The author has an hindex of 2, co-authored 2 publications receiving 111 citations. Previous affiliations of Gabrielle E. Ahlzadeh include University of California, Los Angeles.
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Journal ArticleDOI
Gene therapy-mediated delivery of targeted cytotoxins for glioma therapeutics
Marianela Candolfi,Weidong Xiong,Kader Yagiz,Chunyan Liu,Akm Ghulam Muhammad,Mariana Puntel,David Foulad,Ali Zadmehr,Gabrielle E. Ahlzadeh,Kurt M. Kroeger,Matthew Tesarfreund,Sharon Lee,Waldemar Debinski,Dhruv Sareen,Clive N. Svendsen,Ronald Rodriguez,Pedro R. Lowenstein,Maria G. Castro +17 more
TL;DR: A regulatable adenoviral vector encoding a mutated human IL-13 fused to Pseudomonas exotoxin that specifically binds to IL13Rα2 to provide sustained expression, effective anti-GBM cytotoxicity, and minimal neurotoxicity is developed, representing a significant advance in the development of targeted therapeutics for GBM.
Journal ArticleDOI
Temozolomide Does Not Impair Gene Therapy-Mediated Antitumor Immunity in Syngeneic Brain Tumor Models
Marianela Candolfi,Kader Yagiz,Mia Wibowo,Gabrielle E. Ahlzadeh,Mariana Puntel,Homayon Ghiasi,Neha Kamran,Christopher Paran,Pedro R. Lowenstein,Maria G. Castro +9 more
TL;DR: The results challenge the notion that chemotherapy leads to a state of immune-suppression which impairs the ability of the immune system to mount an effective antitumor response and supports its clinical implementation in combination with immune-mediated therapies.
Journal ArticleDOI
FARES Fared Better Than Others, But Is It Really One-Size-Fits-All?
TL;DR: In this article , the authors propose a method to solve the problem of P.P.X. XX, P.X., and P.V.V., P. XX.