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Sharon Lee

Researcher at University of California, Los Angeles

Publications -  6
Citations -  206

Sharon Lee is an academic researcher from University of California, Los Angeles. The author has contributed to research in topics: Medicine & Genetic enhancement. The author has an hindex of 3, co-authored 4 publications receiving 188 citations.

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Gene therapy-mediated delivery of targeted cytotoxins for glioma therapeutics

TL;DR: A regulatable adenoviral vector encoding a mutated human IL-13 fused to Pseudomonas exotoxin that specifically binds to IL13Rα2 to provide sustained expression, effective anti-GBM cytotoxicity, and minimal neurotoxicity is developed, representing a significant advance in the development of targeted therapeutics for GBM.
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Contact lens complications in an urgent-care population: the University of California, Los Angeles, contact lens study.

TL;DR: Symptomatic CL wear–related complications, and specifically MK, strongly correlate with EW with less relation to lens design, material, and wear modality, and it is concluded that CL EW is a risk factor leading to urgent-care visits.
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A functional genomics screen identifying blood cell development genes in Drosophila by undergraduates participating in a course-based research experience

Cory J. Evans, +351 more
TL;DR: A two-phase screen using RNA interference (RNAi) in combination with fluorescent reporter proteins to identify genes important for hematopoiesis in Drosophila was conducted by students participating in the UCLA Undergraduate Research Consortium for Functional Genomics (URCFG) as discussed by the authors.
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Neural activation to peer acceptance and rejection in relation to concurrent and prospective depression risk in adolescent and pre-adolescent girls

TL;DR: In this paper , the authors investigated the neural response to peer rejection and acceptance in relation to concurrent and prospective depression risk in adolescent and pre-adolescent girls and found that greater response to rejection was associated with fewer depressive symptoms at 12-months and mediated the association between high risk group status and 12-month depressive symptoms.