Gad Singer

TL;DR: The apparent restriction of these BRAF and KRAS mutations to low-grade serous ovarian carcinoma and its precursors suggests that low- grade and high-grade ovarian serous carcinomas develop through independent pathways.

TL;DR: The morphologic, immunohistochemical, and molecular genetic analysis comparing SBTs with low- and high-grade serous carcinomas suggests a common lineage for SBTs and low-grade invasive serious carcinomas and supports the view that SBTs are unrelated to the usual type of invasiveserous carcinoma, which is a high- grade neoplasm.

TL;DR: A dualistic model for ovarian serous carcinogenesis is proposed that involves a stepwise progression from SBT to noninvasive and then invasive MPSC and is characterized by rapid progression from the ovarian surface epithelium or inclusion cysts to a conventional (high-grade) serous cancers.

TL;DR: The first ex vivo images of fresh, native breast tissue obtained from mastectomy specimens using grating interferometry are presented, presenting improved diagnostic capabilities when compared with conventional mammography, especially when discerning the type of malignant conversions and their breadth within normal breast tissue.

TL;DR: The findings suggest that measurement of sHLA-G is a useful molecular adjunct to cytology in the differential diagnosis of malignant versus benign ascites.