G
Gaetano Di Chiara
Researcher at University of Cagliari
Publications - 133
Citations - 15635
Gaetano Di Chiara is an academic researcher from University of Cagliari. The author has contributed to research in topics: Dopamine & Nucleus accumbens. The author has an hindex of 61, co-authored 133 publications receiving 15105 citations. Previous affiliations of Gaetano Di Chiara include National Research Council.
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Cannabinoid and Heroin Activation of Mesolimbic Dopamine Transmission by a Common µ1 Opioid Receptor Mechanism
TL;DR: Delta9-THC and heroin exert similar effects on mesolimbic dopamine transmission through a common mu1 opioid receptor mechanism located in the ventral mesencephalic tegmentum.
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Nucleus accumbens shell and core dopamine: differential role in behavior and addiction
TL;DR: An associative learning hypothesis is proposed according to which stimuli contingent upon drug reward acquire powerful incentive properties after a relatively limited number of predictive associations with the drug and become particularly resistant to extinction.
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Dopamine and Drug Addiction: The Nucleus Accumbens Shell Connection
Gaetano Di Chiara,Valentina Bassareo,Sandro Fenu,Maria Antonietta De Luca,Liliana Spina,C Cadoni,Elio Maria Gioachino Acquas,E. Carboni,Valentina Valentini,Daniele Lecca +9 more
TL;DR: It is speculated that drug addiction results from the impact exerted on behavior by the abnormal DA stimulant properties acquired by drug-conditioned stimuli as a result of their association with addictive drugs.
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Role of dopamine in the behavioural actions of nicotine related to addiction
TL;DR: In vivo monitoring studies show that nicotine stimulates dopamine transmission in specific brain areas and in particular, in the shell of the nucleus accumbens and in areas of the extended amygdala, suggesting that nicotine depends on dopamine for those behavioural effects that are most relevant for its reinforcing properties and are likely to be the basis of the abuse liability of tobacco smoke.
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The role of dopamine in drug abuse viewed from the perspective of its role in motivation
TL;DR: Dopamine is involved in the induction and in the expression of behavioural sensitization by repeated exposure to various drugs of abuse, and might be instrumental for the acquisition of responding to drug-related incentive stimuli (incentive learning).