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Gail S. Harrison

Researcher at University of Colorado Denver

Publications -  26
Citations -  1484

Gail S. Harrison is an academic researcher from University of Colorado Denver. The author has contributed to research in topics: Silibinin & Transfection. The author has an hindex of 18, co-authored 26 publications receiving 1414 citations. Previous affiliations of Gail S. Harrison include Anschutz Medical Campus & Roosevelt Institute.

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Journal ArticleDOI

A phase I and pharmacokinetic study of silybin-phytosome in prostate cancer patients.

Thomas W. Flaig, +8 more
- 01 Nov 2006 - 
TL;DR: It is concluded that 13 g of oral silybin-phytosome daily, in 3 divided doses, appears to be well tolerated in patients with advanced prostate cancer and is the recommended phase II dose.
Journal Article

A DNA cassette containing a trimerized SV40 polyadenylation signal which efficiently blocks spurious plasmid-initiated transcription.

Ian H. Maxwell, +3 more
- 01 Mar 1989 - 
TL;DR: A head-to-tail trimer of the SV40 Bcl I-Bam H1 DNA fragment, specifying polyadenylation of RNA transcripts, was cloned as a cassette flanked by multiple restriction sites to prevent spurious expression of reporter genes resulting from transcriptional initiation in prokaryotic plasmid sequences in transfected mammalian cells.
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A study of high-dose oral silybin-phytosome followed by prostatectomy in patients with localized prostate cancer.

Thomas W. Flaig, +12 more
- 01 Jun 2010 - 
TL;DR: The purpose of the current trial was to determine the tissue and blood effects of high‐dose silybin‐phytosome in prostate cancer patients.
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Silibinin causes cell cycle arrest and apoptosis in human bladder transitional cell carcinoma cells by regulating CDKI-CDK-cyclin cascade, and caspase 3 and PARP cleavages.

Alpana Tyagi, +4 more
- 01 Sep 2004 - 
TL;DR: It is suggested that silibinin modulates CDKI-CDK-cyclin cascade and activates caspase 3 causing growth inhibition and apoptotic death of human TCC cells, providing a strong rationale for future studies evaluating preventive and/or intervention strategies for silib inin in bladder cancer pre-clinical models.
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Chromosomal location of human genes encoding major heat-shock protein HSP70.

Gail S. Harrison, +10 more
- 01 Mar 1987 - 
TL;DR: It is demonstrated that functional genes encoding HSP70 proteins map to human chromosomes 6, 14, 21, and at least one other chromosome.