G
Gang Chen
Researcher at Shenyang Pharmaceutical University
Publications - 32
Citations - 606
Gang Chen is an academic researcher from Shenyang Pharmaceutical University. The author has contributed to research in topics: Apoptosis & Glycoside. The author has an hindex of 11, co-authored 32 publications receiving 374 citations. Previous affiliations of Gang Chen include Guangxi Normal University & Kyoto Pharmaceutical University.
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Journal ArticleDOI
Ionic Liquid Solutions as a Green Tool for the Extraction and Isolation of Natural Products.
Jiao Xiao,Gang Chen,Ning Li +2 more
TL;DR: The application of ILs to rich the extraction of critical bioactive constituents that were reported possessing multiple therapeutic effects or pharmacological activities, from medicinal plants are described to further reduce the environmental damage caused by large quantity of organic chemical reagents.
Journal ArticleDOI
A natural chalcone induces apoptosis in lung cancer cells: 3D-QSAR, docking and an in vivo/vitro assay.
Gang Chen,Di Zhou,Xuezheng Li,Zhe Jiang,Chengyu Tan,Xiu-Yan Wei,Junhong Ling,Jing Jing,Fen Liu,Ning Li +9 more
TL;DR: The results suggest that lonchocarpin is a potentially useful natural agent for cancer treatment.
Journal ArticleDOI
Lico A Causes ER Stress and Apoptosis via Up-Regulating miR-144-3p in Human Lung Cancer Cell Line H292.
Gang Chen,Yue-Ping Ma,Yue-Ping Ma,Zhe Jiang,Yuan Feng,Yuan Feng,Yueqing Han,Yueqing Han,Yetian Tang,Yetian Tang,Zhang Juan,Ni Hui,Xuezheng Li,Ning Li,Ning Li +14 more
TL;DR: The results suggested thatLico A could cause UPR, autophagy and apoptosis, and the underlying mechanism involved up-regulation of miR-144-3p, and increased lico A level would also increase the potential for Lico A inhibiting CHOP-dependent apoptosis in H292 cells.
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Sesquiterpene Coumarins from Ferula sinkiangensis Act as Neuroinflammation Inhibitors.
TL;DR: A bioactivity-guided phytochemical research was performed on the traditional Chinese medicine "Awei", that exhibited a significant inhibitory effect on nitric oxide production in over-activated microglia cells, and identified sixteen bioactive sesquiterpene coumarins in the effective extract of Ferula sinkiangensis.
Journal ArticleDOI
Brazilian Natural Medicines. IV. New Noroleanane-Type Triterpene and Ecdysterone-Type Sterol Glycosides and Melanogenesis Inhibitors from the Roots of Pfaffia glomerata
Seikou Nakamura,Gang Chen,Gang Chen,Souichi Nakashima,Hisashi Matsuda,Yue-Hu Pei,Masayuki Yoshikawa +6 more
TL;DR: The ethyl acetate and 1-butanol soluble fractions of the roots of Pfaffia glomerata were found to show inhibitory effects on melanogenesis in theophylline-stimulated B16 melanoma 4A5 cells, and a new noroleanane-type triterpene, pfaffianol A, its glycoside, and ecdysterone-type sterol glycosides were isolated.