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Seikou Nakamura

Researcher at Kyoto Pharmaceutical University

Publications -  217
Citations -  4980

Seikou Nakamura is an academic researcher from Kyoto Pharmaceutical University. The author has contributed to research in topics: Triterpene & Oleanane. The author has an hindex of 38, co-authored 204 publications receiving 4371 citations.

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Medicinal flowers. XII.(1)) New spirostane-type steroid saponins with antidiabetogenic activity from Borassus flabellifer.

TL;DR: From the methanolic extract from the male flowers of Borassus flabellifer, six new spirostane-type steroid saponins, borassosides A-F, were isolated together with 23 known constituents and their structures were elucidated on the basis of chemical and physicochemical evidences.
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New type of anti-diabetic compounds from the processed leaves of Hydrangea macrophylla var. thunbergii (Hydrangeae Dulcis Folium).

TL;DR: Hydrangenol, a principal constituent, significantly increased the amount of adip onectin released into the medium and mRNA levels of adiponectin, peroxisome proliferator-activated receptor gamma2 (PPARgamma2), and glucose transporter 4 (GLUT4), while it decreased the expression of interleukin 6 (IL-6) mRNA.
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Melanogenesis inhibitors from the desert plant Anastatica hierochuntica in B16 melanoma cells.

TL;DR: The methanolic extract from the whole plants of Anastatica hierochuntica, an Egyptian herbal medicine, was found to inhibit melanogenesis in theophylline-stimulated murine B16 melanoma 4A5 cells and the inhibition of tyrosinase activity suggested to be important.
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Phenylethanoid oligoglycosides and acylated oligosugars with vasorelaxant activity from Cistanche tubulosa.

TL;DR: The methanolic extract from the dried stems of Cistanche tubulosa (Schrenk) R. Wight was found to show an inhibitory effect on contractions induced by noradrenaline in isolated rat aortic strips.
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Melanogenesis inhibitors from the rhizomes of Alpinia officinarum in B16 melanoma cells.

TL;DR: The 80% aqueous acetone extract from the rhizomes of Alpinia officinarum, a Chinese medicinal herb, were found to inhibit melanogenesis in theophylline-stimulated murine B16 melanoma 4A5 cells.