Garry Wong

TL;DR: The SOM algorithm is applied to analyze published data of yeast gene expression and it is shown that SOM is an excellent tool for the analysis and visualization of gene expression profiles.

TL;DR: This transgenic model in C. elegans, an invertebrate organism with excellent experimental resources for further genetic manipulation, may help facilitate dissection of pathophysiologic mechanisms of various synucleopathies.

TL;DR: Five key trends were observed: miRNA identification and target prediction have been hot spots in the past decade; manual curation and TM are the main methods for collecting miRNA knowledge from literature; most early tools are well maintained and widely used; however, novel ones have begun to emerge and disease-associated miRNA tools are emerging.

TL;DR: It is shown that the SOM visualizes the similarity of genes in a more trustworthy way than two alternative methods, multidimensional scaling and hierarchical clustering.

TL;DR: It is reported here that BDNF regulates the cell surface levels of transfected or endogenously expressed full-length TRKB, depending on the exposure time in neuroblastoma cells and primary hippocampal neurons, and suggests that regulation of TRKB surface expression levels by different factors is tightly controlled by complex mechanisms in active neurons.